121032-78-8

Basic information

• Product Name: 3-(Hydroxy-phenyl-methyl)-4,5,6,7-tetrahydro-3H-isobenzofuran-1-one
• Synonyms: 3-(Hydroxy-phenyl-methyl)-4,5,6,7-tetrahydro-3H-isobenzofuran-1-one
• CAS NO: 121032-78-8
• Molecular Weight: 244.29
• Mol File: 121032-78-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(Hydroxy-phenyl-methyl)-4,5,6,7-tetrahydro-3H-isobenzofuran-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Hydroxy-phenyl-methyl)-4,5,6,7-tetrahydro-3H-isobenzofuran-1-one(121032-78-8)
• EPA Substance Registry System: 3-(Hydroxy-phenyl-methyl)-4,5,6,7-tetrahydro-3H-isobenzofuran-1-one(121032-78-8)

Safety Data

• Hazardous Substances Data: 121032-78-8(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 76539-22-5 (2-chloro-1-cyclohexen-1-yl)methanol 
• 100-52-7 benzaldehyde 
• 1680-73-5 2-chlorocyclohexene-1-carboxaldehyde 

Downstream Products

• 56475-18-4 3-benzylidene-4,5,6,7-tetrahydro-3H-isobenzofuran-1-one 

Relevant articles and documents

Carbonylation of Vinyl Halides with Carbonylcobalt

The reactions of both (E)-β-bromostyrene (E)-(1a) and its Z-isomer (Z)-(1a) with octacarbonyldicobalt in the presence of methyl iodide and calcium hydroxide at 20 deg C in dioxane-water under carbon monoxide (1 atm) gave (E)-cinnamic acid (E)-(2a) exclusively.In contrast, with (E)-1-bromo-2-phenylpropene (E)-(1b), the thermodynamically less stable (Z)-3-phenylbut-2-enoic acid (Z)-(2b) was obtained as the major product together with the (E)-isomer (E)-(2b).The carbonylation of 3-chloroprop-2-enols (7a-f) gave the corresponding furan-2(5H)-ones (8a-f) in good yield.