1215037-58-3

Basic information

• Product Name: C₁₅H₁₈O₆
• Synonyms: C₁₅H₁₈O₆
• CAS NO: 1215037-58-3
• Molecular Weight: 294.304
• Mol File: 1215037-58-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₈O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₈O₆(1215037-58-3)
• EPA Substance Registry System: C₁₅H₁₈O₆(1215037-58-3)

Safety Data

• Hazardous Substances Data: 1215037-58-3(Hazardous Substances Data)

Upstream product

• 90-53-9 2,3-dimethoxyphenylacetic acid 
• 140-88-5 ethyl acrylate 

Relevant articles and documents

Ligand-accelerated C-H activation reactions: Evidence for a switch of mechanism

Initial rate studies have revealed dramatic acceleration in aerobic Pd(II)-catalyzed C-H olefination reactions of phenylacetic acids when mono-N-protected amino acids are used as ligands. In light of these findings, systematic ligand tuning was undertaken, which has resulted in drastic improvements in substrate scope, reaction rate, and catalyst turnover. We present evidence from intermolecular competition studies and kinetic isotope effect experiments that implies that the observed rate increases are a result of acceleration in the C-H cleavage step. Furthermore, these studies suggest that the origin of this phenomenon is a change in the mechanism of C-H cleavage from electrophilic palladation to proton abstraction.