1220779-37-2Relevant articles and documents
Concise total syntheses of aspalathin and nothofagin
Yepremyan, Akop,Salehani, Baback,Minehan, Thomas G.
supporting information; experimental part, p. 1580 - 1583 (2010/06/17)
Chemical Fig. Reprentation Syntheses of the C-glycosyl flavone natural products aspalathin and nothofagin have been accomplished in eight steps from tribenzyl glucal, tribenzylphloroglucinol, and either 4-(benzyloxy) phenylacetylene or 3,4-bis(benzyloxy)phenylacetylene. The key step of the syntheses involves a highly stereoselective Lewis acid promoted coupling of 1,2-di-o-acyl-3,4,6-tribenzylglucose with tribenzylphloroglucinol, which gives rise to the corresponding β-C-aryl glycoside in 30-65% yields.