1229705-85-4

Basic information

• Product Name: 5-methyl-1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2(1H)-pyridinone
• Synonyms: 5-methyl-1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2(1H)-pyridinone
• CAS NO: 1229705-85-4
• Molecular Weight: 285.343
• Mol File: 1229705-85-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-methyl-1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2(1H)-pyridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2(1H)-pyridinone(1229705-85-4)
• EPA Substance Registry System: 5-methyl-1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2(1H)-pyridinone(1229705-85-4)

Safety Data

• Hazardous Substances Data: 1229705-85-4(Hazardous Substances Data)

Upstream product

• 1003-68-5 5-methyl-2-pyridone 
• 36603-49-3 4-(tetrahydropyran-2'-yloxy)-1-bromobenzene 
• 110-87-2 3,4-dihydro-2H-pyran 
• 106-41-2 4-bromo-phenol 
• 1437615-55-8 tris(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)bismuthine 

Downstream Products

• 851518-71-3 1-(4-hydroxyphenyl)-5-methylpyridine-2(1H)-one 

Relevant articles and documents

Phosphoramidate prodrug of nucleoside analogues, a pharmaceutical composition and applications of the phosphoramidate prodrug

The invention relates to phosphoramidate prodrug of nucleoside analogues, or stereoisomers of the phosphoramidate prodrug, or a mixture of the stereoisomers of the phosphoramidate prodrug, or pharmaceutically acceptable salts or solvates of the phosphoramidate prodrug, and applications in the preparation of medicine for preventing or treating hepatitis B virus (HBV) and/or human immunodeficiency virus (HIV) infection alone or in combination with other medicine. The anti-HBV activity of the compound of the invention is equivalent to that of tenofovir alafenamide fumarate (TAF), and the compoundof the invention has the anti-liver fibrosis effect, can help improve the therapeutic effect of patients, and has good safety important clinical significance.