123499-58-1Relevant articles and documents
Enzymatic ADP-ribosylation of Benzotriazoles and Related Triazoles. Difference of Glycosidation Site between Triazoles and Indazoles
Tono-oka, Shuichi,Azuma, Ichiro
, p. 339 - 343 (2007/10/02)
Some benzotriazoles and related triazole were ADP-ribosylated in the presence of NAD and NAD-nucleosidase to give corresponding dinucleotides.The site of ribosylation for these dinucleotides was found exclusively to be N-1 on the basis of their uv and 15N-nmr spectra, contrasting with N-2 for indazole dinucleotides.The origin of this difference in regiochemical specificity between the triazole and diazole systems is discussed.