1236-09-5 Usage
Description
Pregn-5-ene-3,20-dione, also known as pregnane, is a C21-steroid that features a double bond between positions 5 and 6 and is substituted by oxo groups at positions 3 and 20. It is a significant compound in the field of pharmaceuticals and medicine due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
Pregn-5-ene-3,20-dione is used as a key intermediate in the synthesis of various steroidal drugs for its ability to be chemically modified to produce a range of therapeutic agents. Its versatile structure allows for the development of medications targeting diverse medical conditions.
Used in Hormone Replacement Therapy:
In the medical field, pregn-5-ene-3,20-dione is used as a precursor in the production of hormone replacement therapies, specifically for the treatment of adrenal insufficiency and other hormone-related disorders. Its role in hormone synthesis makes it a critical component in maintaining endocrine balance.
Used in Contraceptive Development:
Pregn-5-ene-3,20-dione is utilized as a starting material in the development of contraceptives, particularly oral contraceptives. Its hormonal properties allow for the regulation of reproductive functions, providing a means to prevent unwanted pregnancies.
Used in Anti-inflammatory and Immunosuppressive Agents:
pregn-5-ene-3,20-dione is also used as a precursor in the synthesis of anti-inflammatory and immunosuppressive drugs. Its ability to modulate the immune response and reduce inflammation makes it a valuable asset in the treatment of autoimmune diseases and conditions characterized by excessive inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 1236-09-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1236-09:
(6*1)+(5*2)+(4*3)+(3*6)+(2*0)+(1*9)=55
55 % 10 = 5
So 1236-09-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,16-19H,5-12H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
1236-09-5Relevant articles and documents
Synthesis of [3α-3H]-Dehydroepiandrosterone and [3α-3H]-pregnenolone
Tait
, p. 221 - 226 (1998)
[3α-3h]-dehydroepiandrosterone ([3α-3h]-3β-hydroxy-5-androsten-17- one) and [3α-3h]-pregnenolone ([3α-3h]-3β-hydroxy-5-pregnen-20-one) were prepared by selective reduction of 3-keto-5-ene intermediates with tritiated sodium borohydride. These were used as substrates to set up a tritium release assay for 3β-hydroxysteroid oxido-reductase and 5→4-ene isomerase (3β- HSD) which is a key enzyme in steroidogenesis.