1236283-08-1

Basic information

• Product Name: N-(4-chlorobenzyl)-2-{(4-chlorobenzyl)-[2-isopropyl-6-methyl-5-(2-trifluoromethylphenylethynyl)-pyrimidin-4-yl]-amino}-acetamide
• Synonyms: N-(4-chlorobenzyl)-2-{(4-chlorobenzyl)-[2-isopropyl-6-methyl-5-(2-trifluoromethylphenylethynyl)-pyrimidin-4-yl]-amino}-acetamide
• CAS NO: 1236283-08-1
• Molecular Weight: 625.521
• Mol File: 1236283-08-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-chlorobenzyl)-2-{(4-chlorobenzyl)-[2-isopropyl-6-methyl-5-(2-trifluoromethylphenylethynyl)-pyrimidin-4-yl]-amino}-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorobenzyl)-2-{(4-chlorobenzyl)-[2-isopropyl-6-methyl-5-(2-trifluoromethylphenylethynyl)-pyrimidin-4-yl]-amino}-acetamide(1236283-08-1)
• EPA Substance Registry System: N-(4-chlorobenzyl)-2-{(4-chlorobenzyl)-[2-isopropyl-6-methyl-5-(2-trifluoromethylphenylethynyl)-pyrimidin-4-yl]-amino}-acetamide(1236283-08-1)

Safety Data

• Hazardous Substances Data: 1236283-08-1(Hazardous Substances Data)

Upstream product

• 1236282-84-0 N-(4-chlorobenzyl)-2-[(4-chlorobenzyl)-(5-iodo-2-isopropyl-6-methylpyrimidin-4-yl)-amino]-acetamide 
• 704-41-6 1-ethynyl-2-(trifluoromethyl)benzene 

Downstream Products

• 1236283-47-8 7-(4-chlorobenzyl)-2-isopropyl-4-methyl-5-(2-trifluoromethylbenzoyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid 4-chlorobenzylamide 

Relevant articles and documents

Toward Pyrrolo[2,3- d ]pyrimidine scaffolds

(Figure presented) Herein, we present a new route to highly substituted pyrrolo[2,3-d]pyrimidines featuring a Ugi-Smiles/Sonogashira cascade followed by an efficient base-catalyzed intramolecular cyclization. When formaldehyde is chosen as input in the Ugi-Smiles step, aromatic fused systems are eventually obtained through the isomerization of an exo-alkylidene intermediate.