124-30-1 Usage
Description
Octadecanamine, also known as N-stearylamine or 1-aminooctadecane, is an 18-carbon primary aliphatic amine belonging to the class of organic compounds known as monoalkylamines. It is a very strong basic compound with a white waxy crystalline solid appearance and exhibits alkalinity. Octadecanamine is soluble in chloroform, alcohol, ether, and benzene, slightly soluble in acetone, and insoluble in water. It is less dense than water, hence floats on water, and contact may irritate skin, eyes, and mucous membranes. It may be toxic by ingestion and is used to make other chemicals.
Uses
Used in Organic Synthesis:
Octadecanamine is used as an intermediate in organic synthesis for the production of octadecyl quaternary ammonium salts and various additives such as cationic grease thickeners, mineral flotation agents, pesticides, asphalt emulsifiers, fabric antistatic agents, softeners, wetting agents, waterproofing agents, surfactants, biocides, color formers of color photo, and corrosion inhibitors of oil refining devices.
Used in the Production of Stearyl Diethanolamine:
By reacting Octadecanamine with ethylene oxide in a molar ratio of 1:2 at 150-190°C, stearyl diethanolamine [10213-78-2] can be produced with a yield of 80%. Stearyl diethanolamine is a non-ionic antistatic agent that can be applied to polypropylene, polystyrene, and ABS resin.
Used in Biological Studies:
Octadecanamine is utilized in biological studies for the formation of ion pairing as an alternative to improve encapsulation and stability and to reduce skin irritation of retinoic acid loaded in solid lipid nanoparticles.
Used in Surface Functionalization of Carbon Nanomaterials:
Octadecanamine is employed to surface functionalize different carbon nanomaterials, such as graphene oxide and carbon nanotubes, for applications including thin film nanocomposite (TFN) nanofiltration and carbon fiber microelectrodes. It is also used in the preparation of butyrylcholinesterase/stearylamine films (Langmuir-Blodgett films) for use in enzymatic field-effect transistor (ENFET) based biosensors. Additionally, Octadecanamine forms films that can be used in ion exchange systems and in the preparation of metal oxide nano crystals with controlled size and shape.
Used in Nanodiamond Surface Modification:
Octadecanamine (ODA) is used to induce hydrophobicity in nanodiamond (ND) powders.
Used in Graphite and Fullerene Surface Modification:
ODA is also utilized in the surface modification of graphite and fullerenes.
Used as a Dual Source of Carbon and Nitrogen:
ODA serves as a dual source of carbon and nitrogen in the synthesis of N-doped carbon nanotubes (CNTs).
Used in the Synthesis of Cationic Surfactants:
ODA is employed to synthesize a single-chain cationic surfactant, bis(amidoethylcarbamoylethyl) octadecylamine.
Octadecanamine
Octadecanamine (Stearyl amine or 1-amino-octadecane) is a kind of aliphatic amines compound being subject to industrial mass production. At room temperature, it is as white crystals with the molecular weight being 269.5, melting point being 52.8612, boiling point being 232.12 (4.27 kPa), the flash point being 149 ℃, the relative density being 0.8618 and the refractive index being 1.4522. It is slightly soluble in acetone, kerosene and methanol, easily soluble in carbon tetrachloride, chloroform, ethanol, isopropanol and toluene, soluble in alcohol, ether, benzene but insoluble in water. It has alkaline property and can react with hydrochloric acid to generate adduct product. Its toxicity is lower than low-grade amine. Rat being subject to oral administration of 500 × 10-6 Octadecanamine for two consecutive years get no significant adverse consequences. It has irritation effect on human skin and mucous membrane. It can be used as the intermediates for organic synthesis such as for the production of octadecyl quaternary ammonium salts and various kinds of additives such as cationic thickening agent, mineral flotation agents, emulsifier of synthetic resins, pesticides and asphalt, antistatic agents, wetting agents, waterproofing agents, surfactants as well as biocides of fabric, color former of color photo and the corrosion inhibitor of the oil refining device. It can be generated by the reaction of stearic acid and ammonia for generating octadecanitrile and further catalytic hydrogenation under pressure for further reduction of enamine.
The raw material for preparation of softener D3
Softener D3 has its scientific name being N-octadecyl-amino ethyl propionate and belongs to amphoteric surfactants. Common product appears as a white or pale yellow paste-like with the solid content being 20% ± 1% and the pH value of the 2% aqueous solution being 7.0 to 8.0. It can be dissolved in warm water of 50~60 ℃This product is non-toxic, non-corrosive and is mainly used as an additive upon finishing of real silk fabric. It can also be used as the softening finishing agent of silk, wool and chemical fiber. Finishing with it can make the fabrics feel soft, smooth and appear plump, shiny and bright and can also give the fabric elasticity and improve the flex abrasion which can tolerate high temperature of 180 ℃. It can be produced through the condensation reaction between Octadecanamine and methyl acrylate at 80 ℃ and further saponification with triethanolamine and Peregal O.
Raw materials for preparation of dye leveler DC
Dye leveler DC has its chemical name be the octadecyl dimethyl benzyl ammonium chloride. At room temperature, it appears as light yellow sticky liquid and is soluble in water with the pH of its 0.1% aqueous solution being 5.2 to 5.5. It is capable of tolerating the hard water, inorganic salts and acids but not alkali. This product is cationic and has a strong affinity to the acrylic fibers with excellent dye leveling effect on the cationic dyes. It is mainly used as the dye-leveling agent in case of application of cationic dye for dyeing a variety of acrylic fibers and for giving a good hand feeling. The common amount is usually 2% to 3% of the weight of the fabric upon light color while being 0.8% to 1.5% upon dark color.
The product also can be used as the softening agents of cellulose acetate as well as sanitizers. It can be produced through the methylation reaction of Octadecanamine and its further reaction with benzyl chloride.
The above information is edited by the lookchem of Dai Xiongfeng.
Production method
It can be obtained from stearic acid via ammoniation and hydrogenation. Send stearic acid and ammonia continuously and quantitatively into the liquid phase reaction tower for ammoniation at 350 ℃ to generate octadecane nitrile. After washing with water and refinement, it was sent to the autoclave and was subject to hydrogenation reaction under 130 ℃ and the pressure of about 3.5MPa with the nickel catalyst for generation of Octadecanamine. The hydrogenated product was subject to precipitation for removing the catalyst to derive the final products. During laboratory preparation, the octadecane nitrile and anhydrous ethanol are subject to boiling under reflux and further put into sodium metal for reaction. Pour the reaction mixture into the dilute hydrochloric acid with cooling obtaining the Octadecanamine hydrochloride. Further treat with 20% sodium hydroxide solution treated with 20% sodium hydroxide solution can produce Octadecanamine. The yield is 85%. Fixed consumption amount of material: stearic acid: 1165kg/t, ammonia 151kg/t, hydrogen gas: 211m3, nickel catalyst: 6kg/t.
Production Methods
Octadecylamine is manufactured under the
trade names of Adogen 142D (Ashland), Alamine 7D
(General Mills), Armeen 18D (Armak), Kemamine P-
990D (Humko), and Jetamine 18D (Jetco).
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Octadecanamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: Exposure to Octadecanamine may cause sensitization of the skin.
Fire Hazard
Octadecanamine is combustible.
Flammability and Explosibility
Nonflammable
Safety Profile
Poison by
intraperitoneal route. Moderately toxic by
ingestion. A skin irritant. When heated to
decomposition it emits toxic fumes of NOx.
See also AMINES.
Check Digit Verification of cas no
The CAS Registry Mumber 124-30-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 124-30:
(5*1)+(4*2)+(3*4)+(2*3)+(1*0)=31
31 % 10 = 1
So 124-30-1 is a valid CAS Registry Number.
InChI:1S/C18H39N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h2-19H2,1H3
124-30-1Relevant articles and documents
Microwave-Assisted Method for the Synthesis of Perylene Ester Imides as a Gateway Toward Unsymmetrical Perylene Bisimides
Gupta, Ravindra Kumar,Achalkumar, Ammathnadu S.
, p. 6290 - 6300 (2018)
A high yielding microwave-assisted synthetic method to obtain unsymmetrical perylene diester monoimide (PEI) by treating the perylene tetrester (PTE) with a requisite amine is reported. Perylene-based molecules are widely used in the construction of self-assembled supramolecular structures because of their propensity to aggregate under various conditions. In comparison to perylene bisimides (PBIs), PEIs are less studied in organic electronics/self-assembly due to the synthetic difficulty and low yields in their preparation. PEIs are less electron deficient and have an unsymmetric structure in comparison to PBIs. Further, the PEIs have a higher solubility than PBIs. The present method is applicable with a wide range of substrates like aliphatic, aromatic, benzyl amines, PTEs, and bay-annulated PTEs. This method provides a tuning handle for the optical/electronic properties of perylene derivatives and also provides an easy access to unsymmetrical PBIs from the PEIs.
Selective Transformations of Triglycerides into Fatty Amines, Amides, and Nitriles by using Heterogeneous Catalysis
Jamil, Md. A. R.,Siddiki, S. M. A. Hakim,Touchy, Abeda Sultana,Rashed, Md. Nurnobi,Poly, Sharmin Sultana,Jing, Yuan,Ting, Kah Wei,Toyao, Takashi,Maeno, Zen,Shimizu, Ken-ichi
, p. 3115 - 3125 (2019/04/26)
The use of triglycerides as an important class of biomass is an effective strategy to realize a more sustainable society. Herein, three heterogeneous catalytic methods are reported for the selective one-pot transformation of triglycerides into value-added chemicals: i) the reductive amination of triglycerides into fatty amines with aqueous NH3 under H2 promoted by ZrO2-supported Pt clusters; ii) the amidation of triglycerides under gaseous NH3 catalyzed by high-silica H-beta (Hβ) zeolite at 180 °C; iii) the Hβ-promoted synthesis of nitriles from triglycerides and gaseous NH3 at 220 °C. These methods are widely applicable to the transformation of various triglycerides (C4–C18 skeletons) into the corresponding amines, amides, and nitriles.
A Mild and Base-Free Protocol for the Ruthenium-Catalyzed Hydrogenation of Aliphatic and Aromatic Nitriles with Tridentate Phosphine Ligands
Adam, Rosa,Bheeter, Charles Beromeo,Jackstell, Ralf,Beller, Matthias
, p. 1329 - 1334 (2016/04/20)
A novel protocol for the general hydrogenation of nitriles in the absence of basic additives is described. The system is based on the combination of [Ru(cod)(methylallyl)2] (cod=cyclooctadiene) and L2. A variety of aromatic and aliphatic nitriles is hydrogenated under mild conditions (50 °C and 15 bar H2) with this system. Kinetic studies revealed higher activity in the case of aromatic nitriles compared with aliphatic ones.