1241959-36-3

Basic information

• Product Name: (2S,3S,4R,5S)-tert-butyl 2-((benzyloxy)methyl)-5-(tert-butyldiphenylsilyloxy)-3,4-dihydroxypiperidine-1-carboxylate
• Synonyms: (2S,3S,4R,5S)-tert-butyl 2-((benzyloxy)methyl)-5-(tert-butyldiphenylsilyloxy)-3,4-dihydroxypiperidine-1-carboxylate
• CAS NO: 1241959-36-3
• Molecular Weight: 591.82
• Mol File: 1241959-36-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S,3S,4R,5S)-tert-butyl 2-((benzyloxy)methyl)-5-(tert-butyldiphenylsilyloxy)-3,4-dihydroxypiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4R,5S)-tert-butyl 2-((benzyloxy)methyl)-5-(tert-butyldiphenylsilyloxy)-3,4-dihydroxypiperidine-1-carboxylate(1241959-36-3)
• EPA Substance Registry System: (2S,3S,4R,5S)-tert-butyl 2-((benzyloxy)methyl)-5-(tert-butyldiphenylsilyloxy)-3,4-dihydroxypiperidine-1-carboxylate(1241959-36-3)

Safety Data

• Hazardous Substances Data: 1241959-36-3(Hazardous Substances Data)

Upstream product

• 1241959-32-9 tert-butyl (3R,6R)-6-((benzyloxy)methyl)-3-((tert-butyldiphenylsilyl)oxy)-3,6-dihydropyridine-1(2H)-carboxylate 
• 1241959-30-7 (R,E)-N-((R)-1-(benzyloxy)but-3-en-2-yl)-2-(tert-butyldiphenylsilyloxy)pent-3-en-1-amine 
• 1241959-31-8 tert-butyl (R)-1-(benzyloxy)but-3-en-2-yl((R,E)-2-(tert-butyldiphenylsilyloxy)pent-3-enyl)carbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1393105-88-8 tert-butyl (2R,5S)-2-(benzyloxymethyl)-5,6-dihydro-5-hydroxypyridine-1(2H)-carboxylate 
• 1393106-15-4 tert-butyl (2R,5R)-2-(benzyloxymethyl)-5,6-dihydro-5-hydroxypyridine-1(2H)-carboxylate 
• 754188-59-5 (5R)-5-[(1R)-2-benzyloxy-1-hydroxyethyl]tetrahydrofuran-2-one 
• 1131711-60-8 (5R,6S)-6-(benzyloxymethyl)-5-hydroxypiperidin-2-one 

Downstream Products

• 1241959-38-5 tert-butyl (2S,3S,4R,5S)-2-(benzyloxymethyl)-3,4,5-trihydroxypiperidine-1-carboxylate 
• 355138-93-1 (2S,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-ium chloride 

Relevant articles and documents

A novel, concise and efficient protocol for non-natural piperidine compounds

Formal synthesis of l-altro-1-deoxynojirimycin, cis-3-hydroxypipecolic acid along with synthesis of (R)-piperidinol and a conceptually different advanced intermediate for non-natural piperidine alkaloids is reported from cis-butene-1,4-diol. The key react

Synthesis of l-altro-1-deoxynojirimycin, d-allo-1-deoxynojirimycin, and d-galacto-1-deoxynojirimycin from a single chiral cyanohydrin

The chemoenzymatic synthesis of three 1-deoxynojirimycin-type iminosugars is reported. Key steps in the synthetic scheme include a Dibal reduction-transimination-sodium borohydride reduction cascade of reactions on an enantiomerically pure cyanohydrin, itself prepared employing almond hydroxynitrile lyase (paHNL) as the common precursor. Ensuing ring-closing metathesis and Upjohn dihydroxylation afford the target compounds.