124356-91-8

Basic information

• Product Name: 2-Oxazolidinone, 3-[(2S,3R)-3-hydroxy-2-methyl-1-oxopentyl]-4-(phenylmethyl)-, (4S)-
• CAS NO: 124356-91-8
• Molecular Formula: C16H21NO4
• Molecular Weight: 291.347
• Mol File: 124356-91-8.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-[(2S,3R)-3-hydroxy-2-methyl-1-oxopentyl]-4-(phenylmethyl)-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-[(2S,3R)-3-hydroxy-2-methyl-1-oxopentyl]-4-(phenylmethyl)-, (4S)-(124356-91-8)
• EPA Substance Registry System: 2-Oxazolidinone, 3-[(2S,3R)-3-hydroxy-2-methyl-1-oxopentyl]-4-(phenylmethyl)-, (4S)-(124356-91-8)

Safety Data

• Hazardous Substances Data: 124356-91-8(Hazardous Substances Data)

Upstream product

• 624-67-9 Propargylic aldehyde 
• 101711-78-8 (3R)-3-propionyl-4-benzyloxazolidin-2-one 
• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 
• 123-72-8 butyraldehyde 
• 133467-37-5 (4S)-3-[(2S,3S)-3-hydroxy-2-methyl-3-phenylpropanoyl]-4-benzyl-2-oxazolidinone 
• 123-38-6 propionaldehyde 

Downstream Products

• 220272-52-6 (S)-4-benzyl-3-((2S,3R)-3-((tert-butyldimethylsilyl)oxy)-2-methylpentanoyl)oxazolidin-2-one 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 145937-04-8 (2S,3R)-3-hydroxy-N-methoxy-N,2-dimethylpentanamide 
• 101712-01-0 (S)-1-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-2-methylpentane-1,3-dione 
• 1439376-72-3 (S)-4-benzyl-3-((2S,3R,4S,5R)-3,5-dihydroxy-2,4-dimethyloct-6-ynoyl)oxazolidin-2-one 

Relevant articles and documents

Synthesis and Biological Evaluation of Dichlorinated Chondramide Derivatives

Straightforward synthetic protocols for the synthesis of new ethyl-substituted dichlorinated chondramides with different methyl-substitution patterns in the polyketide fragment have been developed. The methyl groups at the ?-position can be removed comple

Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides

The gem-dimethyl groups in polyketide-derived natural products add steric bulk, accordingly, lend increased stability to medicinal compounds, however, our ability to rationally incorporate this functional group in modified natural products is limited. In

Racemization of α-Alkyl-β-Keto Esters and Enantioselective Total Synthesis of Two C-2′′′Epimers of Plant Glycerolipid Santinol C

It is broadly believed that optically active α-alkyl-β-keto esters racemize very quickly. Nevertheless, no one really knows how fast the racemization is. In fact, such species are hardly attainable to date. Now, a facile entry to these greatly understudied esters has been found and their racemization has been studied for the first time. The results showed that under neutral or slightly acidic conditions such species were much more stable than one might expect, though they did racemize rapidly under basic conditions. In light of the new findings, santinol C was also synthesized in enantiopure forms.

Concise synthesis and revision of the proposed biogenesis of helicascolides

A concise synthesis of helicascolides A, B and C was achieved in three to five steps from commercially available materials. The key transformations of the synthesis include an Evans-Metternich anti-aldol reaction of the known β-keto imide 10 and strategic