1245526-86-6

Basic information

• Product Name: 1,1,1-trifluoro-4-methyl-4-(3-fluorophenyl)pentan-2-one
• Synonyms: 1,1,1-trifluoro-4-methyl-4-(3-fluorophenyl)pentan-2-one
• CAS NO: 1245526-86-6
• Molecular Weight: 248.22
• Mol File: 1245526-86-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1,1-trifluoro-4-methyl-4-(3-fluorophenyl)pentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-trifluoro-4-methyl-4-(3-fluorophenyl)pentan-2-one(1245526-86-6)
• EPA Substance Registry System: 1,1,1-trifluoro-4-methyl-4-(3-fluorophenyl)pentan-2-one(1245526-86-6)

Safety Data

• Hazardous Substances Data: 1245526-86-6(Hazardous Substances Data)

Upstream product

• 400-31-7 1,1,1-trifluoro-4-methyl-pent-3-en-2-one 
• 17318-03-5 bromo(3-fluorophenyl)magnesium 
• 1073-06-9 3-fluorobromobenzene 

Downstream Products

• 1245526-88-8 6-(3-fluorophenyl)-6-methyl-4-trifluoromethylhept-1-yn-4-ol 
• 1347249-14-2 C₂₄H₂₇F₄N₃O₂ 

Relevant articles and documents

Optimization of drug-like properties of nonsteroidal glucocorticoid mimetics and identification of a clinical candidate

A series of nonsteroidal dissociated glucocorticoid receptor agonists was optimized for drug-like properties such as cytochrome P450 inhibition, metabolic stability, aqueous solubility, and hERG ion channel inhibition. This effort culminated in the identification of the clinical candidate compound (R)-39.