124658-21-5

Basic information

• Product Name: Methyl α-fluoro-α-methylbenzeneacetate
• CAS NO: 124658-21-5
• Molecular Weight: 182.195
• Mol File: 124658-21-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Methyl α-fluoro-α-methylbenzeneacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl α-fluoro-α-methylbenzeneacetate(124658-21-5)
• EPA Substance Registry System: Methyl α-fluoro-α-methylbenzeneacetate(124658-21-5)

Safety Data

• Hazardous Substances Data: 124658-21-5(Hazardous Substances Data)

Upstream product

• 31508-44-8 2-phenylpropionic acid methyl ester 
• 134414-80-5 N-Fluoro-o-benzenedisulfonimide 
• 20731-95-7 methyl 2-hydroxy-2-phenylpropanoate 
• 148600-14-0 methyl 2-azido-2-phenylpropanoate 
• 84892-13-7 methyl 2-bromo-2-phenylpropanoate 
• 87786-35-4 2-bromo-2-phenyl-propionic acid 
• 492-37-5 hydratropic acid 
• 67-56-1 methanol 
• 1026620-12-1 3-Fluoro-2-oxo-3-phenyl-butyronitrile 
• 17841-30-4 methyl (±)-2-fluoro-2-phenylacetate 
• 74-88-4 methyl iodide 
• 88303-12-2 N-fluoro-N-methyl-p-toluene sulfonamide 
• 4507-41-9 2-amino-2-phenyl propanoate de methyle 

Downstream Products

• 199190-98-2 methyl 2-fluoro-3-hydroxy-2-phenylpropanoate 
• 124658-29-3 (S)-3-fluoro-3-phenyl-1-<(4-methylphenyl)sulphenyl>-2-butanone 
• 114107-09-4 (2S,3R)-3-fluoro-3-phenyl-1-<(R)-(4-methylphenyl)sulphinyl>-2-butanol 
• 114182-37-5 (2S,3S)-3-fluoro-3-phenyl-1-<(R)-(4-methylphenyl)sulphinyl>-2-butanol 
• 114107-16-3 (2S,3R)-3-fluoro-3-phenyl-1-<(4-methylphenyl)sulphenyl>-2-butanol 
• 114107-13-0 (2S,3S)-3-fluoro-3-phenyl-1-<(4-methylphenyl)sulphenyl>-2-butanol 
• 114107-21-0 (2R,3R)-3-fluoro-3-phenyl-2-butanol 
• 114130-11-9 (2R,3S)-3-fluoro-3-phenyl-2-butanol 
• 114086-91-8 (3S)-3-fluoro-3-phenyl-1-<(R)-(4-methylphenyl)sulphinyl>-2-butanone 
• 114107-01-6 (3R)-3-fluoro-3-phenyl-1-<(R)-(4-methylphenyl)sulphinyl>-2-butanone 
• 148600-15-1 (+/-)-2-Fluoro-2-phenylpropionic acid 

Relevant articles and documents

N-FLUORO-O-BENZENEDISULFONIMIDE: A USEFUL NEW FLUORINATING REAGENT

N-Fluoro-o-benzenedisulfonimide (5) is a stable, easily prepared, highly efficient source of "electrophilic" fluorine which fluorinates enolates, azaenolates and carbanions in good to excellent yields.

Synthesis of 2-fluoro- acids, esters, and amides from α-dicyanoepoxides

The opening of α-dicyanoepoxides by pyridine polyhydrofluoride yields polymerisable 2-fluorocyanoformyls which may be kept intact when diluated in dichloromethane or ether. These intermediates react with nucleophiles such as water, methanol or amines to give respectively 2-fluoroacids, esters or amides.

Acide 2-fluoro-2-phenyl propanoique: preparation et utilisation comme agent chiral de derivation

The enantiomers of 2-fluoro-2-phenyl propanoic acid have been separated and their absolute configurations determined: the specific rotation of the acid with an R configuration is 20D= -28.5 deg (c=1.5, ethanol).This acid has been