1247027-70-8Relevant articles and documents
Novel carbamate cholinesterase inhibitors that release biologically active amines following enzyme inhibition
Verheijen, Jeroen C.,Wiig, Kjesten A.,Du, Shoucheng,Connors, Stacie L.,Martin, Ashley N.,Ferreira, Jennifer P.,Slepnev, Vladimir I.,Kochendoerfer, Ulrike
, p. 3243 - 3246 (2009)
Conjugation of the phenol derived from rivastigmine with amphetamines gave access to novel carbamate cholinesterase inhibitors. All compounds possessed increased affinity and selectivity for AChE compared to rivastigmine and were orally bioavailable. Comp