1251918-07-6

Basic information

• Product Name: 5,7-dichloro-2-[2-(2,4-dihydroxyphenyl)vinyl]quinolin-8-ol
• Synonyms: 5,7-dichloro-2-[2-(2,4-dihydroxyphenyl)vinyl]quinolin-8-ol
• CAS NO: 1251918-07-6
• Molecular Weight: 348.185
• Mol File: 1251918-07-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,7-dichloro-2-[2-(2,4-dihydroxyphenyl)vinyl]quinolin-8-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-dichloro-2-[2-(2,4-dihydroxyphenyl)vinyl]quinolin-8-ol(1251918-07-6)
• EPA Substance Registry System: 5,7-dichloro-2-[2-(2,4-dihydroxyphenyl)vinyl]quinolin-8-ol(1251918-07-6)

Safety Data

• Hazardous Substances Data: 1251918-07-6(Hazardous Substances Data)

Upstream product

• 72-80-0 chloroquinaldol 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Relevant articles and documents

Investigating the activity spectrum for Ring-Substituted 8-Hydroxyquinolines

In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity. They were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four mycobacterial strains and against eight fungal strains. Several compounds showed biological activity comparable with or higher than the standards isoniazid or fluconazole. For all the compounds, the relationships between the lipophilicity and the chemical structure of the studied compounds are discussed.