1256768-15-6Relevant articles and documents
Abnormal N-heterocyclic carbene promoted Suzuki-Miyaura coupling reaction: A comparative study
Xu, Xiangya,Xu, Baochang,Li, Yongxin,Hong, Soon Hyeok
, p. 6343 - 6349 (2011/02/17)
A C2-protected imidazolium salt that generates an abnormal N-heterocyclic carbene (NHC) was applied for the palladium-catalyzed Suzuki-Miyaura coupling reactions. The abnormal NHC precursor promoted the reactions while suppressing homocoupling of aryl boronic acid, which was observed with the corresponding normal NHC precursor. The related well-defined abnormal NHC-based palladium complexes also showed better activity than the normal NHC-based analogues, exhibiting faster reaction rates especially at the initial stage of the reaction.