1261393-15-0

Basic information

• Product Name: Apixaban-13C-D3
• Synonyms: Apixaban-13C-D3
• CAS NO: 1261393-15-0
• Molecular Formula: C25H22D3N5O4
• Molecular Weight: 463.524585334
• Mol File: 1261393-15-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Apixaban-13C-D3(CAS DataBase Reference)
• NIST Chemistry Reference: Apixaban-13C-D3(1261393-15-0)
• EPA Substance Registry System: Apixaban-13C-D3(1261393-15-0)

Safety Data

• Hazardous Substances Data: 1261393-15-0(Hazardous Substances Data)

Usage

Description

Apixaban-13C-D3 is a stable isotope-labeled derivative of Apixaban, a direct oral anticoagulant used for the prevention and treatment of various thrombotic disorders. The incorporation of 13C and D3 isotopes into the Apixaban molecule allows for accurate quantification and differentiation from endogenous compounds during mass spectrometry analysis.

Uses

Used in Pharmaceutical Analysis:
Apixaban-13C-D3 is used as an internal standard for the quantification of Apixaban by gas chromatography (GC) or liquid chromatography (LC) mass spectrometry. This application is crucial for ensuring the accuracy and reliability of Apixaban measurements in various biological samples, such as blood or plasma, for therapeutic drug monitoring, pharmacokinetic studies, and clinical research.
Used in Clinical Research:
In clinical research, Apixaban-13C-D3 serves as a valuable tool for investigating the pharmacokinetics, pharmacodynamics, and safety profiles of Apixaban. By providing a stable and accurate reference, researchers can better understand the drug's behavior in the body and optimize dosing regimens for improved patient outcomes.
Used in Quality Control:
Apixaban-13C-D3 is also utilized in the quality control of pharmaceutical formulations containing Apixaban. By comparing the mass spectrometry signals of the labeled compound to those of the unlabeled drug, manufacturers can verify the purity, potency, and consistency of their products, ensuring that they meet regulatory standards and provide the desired therapeutic effects.