1276113-10-0Relevant articles and documents
2′-deoxy-2′-α-C-(hydroxymethyl)adenosine as potential anti-HCV agent
Chavain, Natascha,Herdewijn, Piet
, p. 1140 - 1147 (2011/03/22)
Because of the importance of C-branched nucleosides in the discovery of new antiviral molecules, we decided to synthesize 2′-deoxy-2′-α- C-(hydroxymethyl)adenosine as a potential anti-HCV agent. The synthesis of a new adenosine analogue following two different synthetic routes is described. The new C-branched nucleoside was tested for its antiviral activity and found to be inactive.