128837-26-3

Basic information

• Product Name: 4-(ethyloxymethoxy)benzaldehyde
• Synonyms: 4-(ethyloxymethoxy)benzaldehyde
• CAS NO: 128837-26-3
• Molecular Weight: 180.203
• Mol File: 128837-26-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-(ethyloxymethoxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(ethyloxymethoxy)benzaldehyde(128837-26-3)
• EPA Substance Registry System: 4-(ethyloxymethoxy)benzaldehyde(128837-26-3)

Safety Data

• Hazardous Substances Data: 128837-26-3(Hazardous Substances Data)

Upstream product

• 3188-13-4 ethyl chloromethyl ether 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 1226854-44-9 1-(4''-hydroxyphenyl)-3-(3'-hydroxy-2',4'-dimethoxyphenyl)propene 
• 69097-97-8 7,4'-dihydroxy-dihydroflavone 
• 123316-63-2 3'-(isoprenyl)-2',4-dihydroxy-4',6'-dimethoxychalcone 
• 123316-64-3 (E)-4,4'-dihydroxy-2',6'-dimethoxychalcone 
• 808733-43-9 N'-(4-ethoxymethoxy-benzyl)-hydrazinecarboxylic acid 9H-fluoren-9-ylmethyl ester 
• 872554-73-9 N'-[1-(4-Ethoxymethoxy-phenyl)-meth-(E)-ylidene]-hydrazinecarboxylic acid 9H-fluoren-9-ylmethyl ester 
• 302320-77-0 4-ethoxymethoxybenzyl alcohol 
• 158017-93-7 4,4'-diethoxymethoxy-2',6'-dimethoxychalcone 
• 158017-94-8 4-ethoxymethoxy-2'-hydroxy-4',6'-dimethoxy-3'-C-prenylchalcone 
• 961-29-5 isoliquirtigenin 

Relevant articles and documents

Synthetic method of 1,3-substituted Diphenylpropenes

The present invention relates to a method for efficiently synthesizing a natural 1,3-substituted diphenylpropene compound having biological activity. The effective method synthesizes 1,3-substituted diphenylpropene compound 1 to 4 using Friedel-Crafts alk

Facile synthesis and nitric oxide inhibitory activity of aurones, rugaurone a, gramflavonoid a and their derivatives

Facile synthesis of natural aurones, rugaurone A (1a), gramflavonoid A (1b) and their novel derivatives (1c-1o) is accomplished in good to high yields with exceptional Z-selectivity (≥ 97%) from the commercially available starting materials. Herein, practically improved method was developed for the synthesis of common key intermediate, 5,6-dimethoxybenzofuran-3(2H)-one (5). Later, their nitric oxide (NO) production inhibition effects were estimated in lipopolysaccharide (LPS)-induced RAW-264.7 macrophages as an indicator of anti-inflammatory activity. All compounds exhibited weak to good strength against NO production in a concentration-dependent manner and none of the compound showed significant cytotoxicity against macrophages at the highest (10 μM) concentration. The IC50 values are showed in the range from 3.39 to 19.55 μM. Among the 15 aurones synthesized in this study, 3 compounds that is compound 1g (63.98%) followed by compound 1o (49.07%) and rugaurone A (1a) (41.72%) showed the maximum inhibitory activity with respective IC50 values of 4.50 μM, 4.98 μM and 3.39 μM compared to L-NMMA (IC50 = 5.19 μM), which was used as a standard NO inhibitor. This study suggests that compounds 1g, 1o and 1a may serve as favorable structures for further development of NO production-targeted anti-inflammatory agents.

Peptide analogues comprising at least one type of aminoacylaza-γ(b)3and the use thereof, in particular for therapy

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