128839-62-3

Basic information

• Product Name: (4-Butyl-phenyl)-fluoro-acetic acid ethyl ester
• Synonyms: (4-Butyl-phenyl)-fluoro-acetic acid ethyl ester
• CAS NO: 128839-62-3
• Molecular Weight: 238.302
• Mol File: 128839-62-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-Butyl-phenyl)-fluoro-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Butyl-phenyl)-fluoro-acetic acid ethyl ester(128839-62-3)
• EPA Substance Registry System: (4-Butyl-phenyl)-fluoro-acetic acid ethyl ester(128839-62-3)

Safety Data

• Hazardous Substances Data: 128839-62-3(Hazardous Substances Data)

Upstream product

• 128839-56-5 (4-Butyl-phenyl)-hydroxy-acetic acid ethyl ester 
• 401-55-8 ethyl bromofluoroacetate 
• 20651-67-6 4-butyliodobenzene 

Relevant articles and documents

Palladium-Catalyzed Cross-Coupling of Ethyl Bromodifluoroacetate with Aryl Bromides or Triflates and Cross-Coupling of Ethyl Bromofluoroacetate with Aryl Iodides

A palladium-catalyzed Negishi cross-coupling reaction of ethyl bromodifluoroacetate with aryl bromides or aryl triflates to construct C(sp2)-CF2 bonds is described. The reaction was conducted under mild reaction conditions, and no preparation of organozinc reagents is required. This is the first report encompassing the conversion of aryl triflates into products containing C-CF2 bonds. In addition, the construction of C(sp2)-CHF bonds was achieved under mild conditions via a cross-coupling of aryl iodides with ethyl bromofluoroacetate.