1290129-46-2

Basic information

• Product Name: N-2-bromophenyl-N-phenylaminomethane
• Synonyms: N-2-bromophenyl-N-phenylaminomethane
• CAS NO: 1290129-46-2
• Molecular Weight: 262.149
• Mol File: 1290129-46-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-2-bromophenyl-N-phenylaminomethane(CAS DataBase Reference)
• NIST Chemistry Reference: N-2-bromophenyl-N-phenylaminomethane(1290129-46-2)
• EPA Substance Registry System: N-2-bromophenyl-N-phenylaminomethane(1290129-46-2)

Safety Data

• Hazardous Substances Data: 1290129-46-2(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 6832-87-7 2-bromo-N-methylaniline 
• 17763-67-6 Phenyl triflate 
• 100-61-8 N-methylaniline 
• 121-69-7 N,N-dimethyl-aniline 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 583-55-1 1-Bromo-2-iodobenzene 
• 62-53-3 aniline 
• 615-36-1 2-bromoaniline 
• 61613-22-7 2-bromodiphenylamine 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1290129-48-4 9-isopropyl-9,10-dimethyl-9,10-dihydroacridine 
• 87043-43-4 9-ethyl-9-phenyl-10-methyl-9,10-dihydroacridine 
• 99941-46-5 9-methyl-9-phenyl-10-methyl-9,10-dihydroacridine 
• 1290129-51-9 1,1,1,3,3,3-hexafluoro-2-(2-(methyl(phenyl)amino)phenyl)propan-2-ol 
• 58943-96-7 5-methyl-10-phenyl-5,10-dihydrophenophosphazinine 10-oxide 
• 719-54-0 10-methyl-9, 10-dihydro-9-acridinone 

Relevant articles and documents

1,2-Difunctionalization of Aryl Triflates: A Direct and Modular Access to Diversely Functionalized Anilines

ortho-Amino difunctionalization of aryl triflates has been achieved via a three-component reaction. The cascade reaction proceeds through a zincate base-mediated deprotonative formation of a reactive aryne intermediate, in situ nucleophilic addition, and coupling with electrophilic partners. This strategy leverages the advantageous reactivity of organozincate intermediates, enabling the installation of various functionalities such as amine, azide, oxygen, sulfur, halide, alkynyl, aryl, vinyl, and alkyl groups in a modular manner for the synthesis of diverse aniline skeletons.

1,2-Aminohalogenation of arynes with amines and organohalides

An unprecedented use of inexpensive organohalides as halogen electrophiles to trap the zwitterion intermediates generated from amines and arynes has been developed to access structurally diverse tertiary 2-haloanilines. Effective organohalides include carbon tetrachloride, hexachloroethane, N-chlorosuccinimide, carbon tetrabromide, fluorotribromomethane, N-bromosuccinimide, carbon tetraiodide, and N-iodosuccinimide.

A Cu-Catalysed Radical Cross-Dehydrogenative Coupling Approach to Acridanes and Related Heterocycles

The synthesis of acridanes and related compounds through a Cu-catalysed radical cross-dehydrogenative coupling of simple 2-[2-(arylamino)aryl]malonates is reported. This method can be further streamlined to a one-pot protocol involving the in situ fomation of the 2-[2-(arylamino)aryl]malonate by α-arylation of diethyl malonate with 2-bromodiarylamines under Pd catalysis, followed by Cu-catalysed cyclisation.