129207-82-5

Basic information

• Product Name: ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate
• Synonyms: ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate
• CAS NO: 129207-82-5
• Molecular Weight: 311.337
• Mol File: 129207-82-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate(129207-82-5)
• EPA Substance Registry System: ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate(129207-82-5)

Safety Data

• Hazardous Substances Data: 129207-82-5(Hazardous Substances Data)

Upstream product

• 3943-94-0 (E)-ethyl 2-hydroxycinnamate 
• 698-16-8 benzohydroximoyl chloride 

Downstream Products

• 64517-78-8 3-phenyl-4H-<1>benzopyrano<3,4-d>isoxazol-4-one 
• 53256-19-2 ethyl (Z)-3-amino-3-phenylacrylate 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

A Convenient Synthesis of 3-Aryl-4H-benzopyranoisoxazol-4-ones

Regioselective 1,3-dipolar cycloaddition of nitrile oxides 5a-c to ethyl o-hydroxycinnamate (3) gave the corresponding ethyl trans-3-aryl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylates 6a-c.Their structure was confirmed by reductive cleavage to 1 and compounds 9a-c.Compounds 6a-c afforded upon heating in the presence of pyridine the 3-aryl-4H-benzopyranoisoxazol-4-ones 11a-c.Compound 10c was also isolated from 6c and transformed thermally into 11c.