129604-31-5Relevant articles and documents
NEW PROCESS FOR THE PREPARATION OF 2,4,5- TRIFLUOROPHENYLACETIC ACID"
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Paragraph 0050; 0051, (2014/03/24)
The present invention relates to a new process for the preparation of 2,4,5-trifluorophenylacetic acid and salts thereof by means of new synthetic intermediates.
Process for the preparation of fluorinated benzoic acids
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, (2008/06/13)
In the process for the preparation of fluorinated benzoic acids of the formula I STR1 in which X and Y, for example, independently of one another denote chlorine or fluorine and X moreover denotes bromine, a fluorinated chloroacetophenone of the formula II STR2 in which Z denotes chlorine or hydrogen, is reacted with a hypohalite.
Fluorine-containing acetophenones optionally halogenated on the CH3 -group and their precurser fluorine-containing benzonitriles
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, (2008/06/13)
Fluorine-containing acetophenones, optionally halogenated on the CH3 group, of the formula STR1 in which X represents hydrogen, chlorine or bromine and the radicals R1 to R5 have the following meaning, a) R1 and R4 denote fluorine, R2 and R5 denote chlorine and R3 denotes CF3, or b) R1, R3 and R4 denote fluorine and R2 and R5 denote hydrogen, or c) R1, R4 and R5 denote hydrogen, R2 denotes chlorine and R3 denotes CF3, or d) R1, R4 and R5 denote hydrogen, R2 denotes chlorine and R3 denotes OCF3, or e) R1, R4 and R5 denote hydrogen and R2 and R3 denote CF3, or f) R1 denotes chlorine, R2 denotes CF3 and R3, R4 and R5 denote hydrogen, or g) R1 denotes chlorine, R2, R3 and R4 denote hydrogen and R5 denotes CF3, or h) R1 denotes chlorine, R2, R4 and R5 denote hydrogen and R3 denotes CF3 and a process for their preparation from the corresponding fluorinated benzonitriles or benzyl halides by reaction with an organomagnesium compound capable of introducing methyl groups and subsequent hydrolysis, if appropriate followed by a chlorination or bromination.
