130768-87-5

Basic information

• Product Name: 2-Propen-1-one, 1,3-bis(3,4,5-trimethoxyphenyl)-, (2E)-
• CAS NO: 130768-87-5
• Molecular Formula: C21H24O7
• Molecular Weight: 388.417
• Mol File: 130768-87-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1,3-bis(3,4,5-trimethoxyphenyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1,3-bis(3,4,5-trimethoxyphenyl)-, (2E)-(130768-87-5)
• EPA Substance Registry System: 2-Propen-1-one, 1,3-bis(3,4,5-trimethoxyphenyl)-, (2E)-(130768-87-5)

Safety Data

• Hazardous Substances Data: 130768-87-5(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 36266-40-7 1-(3,4,5-trimethoxyhenyl)ethanol 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 

Downstream Products

• 1446353-94-1 3-bromo-2,4-bis-(3,4,5-trimethoxyphenyl)oxetane 
• 1073792-91-2 C₂₂H₂₆N₂O₆S 
• 851729-28-7 3,5-bis(3,4,5-trimethoxyphenyl)-1H-pyrazole 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 

Relevant articles and documents

An organocatalytic asymmetric allylic alkylation allows enantioselective total synthesis of hydroxymetasequirin-a and metasequirin-b tetramethyl ether diacetates

The first highly stereoselective organocatalytic intermolecular allylic alkylation of allylic alcohols with 1,3-dicarbonyls has been developed to allow the first enantioselective total synthesis of hydroxymetasequirin-A and metasequirin-B tetramethyl ethe

NBS-mediated cyclization of trans-cinnamic alcohols

An efficient and straightforward three-step synthetic route toward 2,4-disubstituted-3-bromooxetanes 5 with the trans-trans contiguous stereogenic centers is developed from functionalized chalcones 3 via NaBH 4-mediated reduction of chalcones 3

Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents

A series of substituted chalcones and their corresponding pyrazoles were synthesized and evaluated for in vitro cytotoxic activity against a panel of human cancer cell lines. Out of 93 compounds screened, 8 compounds, 1s, 3i,j,n, 4i,j,n and 4s, showed marked activity. Compounds 4j,n and 4s were found to be the most promising in this study. SAR is also discussed.