13085-50-2 Usage
Description
2'-Deoxycytidine-5'-monophosphate disodium salt, also known as dCMP sodium salt, is a nucleotide monophosphate that plays a crucial role in the biosynthesis of DNA and RNA. It is an essential component in various biological processes and has been widely studied for its applications in different fields.
Uses
Used in Biochemical Research:
2'-Deoxycytidine-5'-monophosphate disodium salt is used as a substrate for uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP. Upon phosphorylation to dCTP, it supports DNA and RNA biosynthesis, making it a vital component in biochemical research and understanding the fundamental processes of cellular replication and transcription.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2'-Deoxycytidine-5'-monophosphate disodium salt is utilized in the development of drugs targeting nucleic acid metabolism. Its role in DNA and RNA synthesis makes it a potential candidate for the treatment of diseases related to nucleic acid synthesis disorders.
Used in Nucleoside Stability Studies:
2'-Deoxycytidine 5'-monophosphate sodium salt has been employed in nucleoside stability studies, specifically in human renal cell carcinoma (RCC) cell line SN12C. This application helps researchers understand the stability and behavior of nucleosides in cancer cells, which can contribute to the development of targeted cancer therapies.
Used in Cell Proliferation Studies:
The compound has also been used in cell proliferation studies of human intestinal Caco-2 cell line and peripheral blood mononuclear cells (PBMCs). These studies are essential for understanding the role of dCMP sodium salt in cell growth and its potential implications in various diseases, including cancer.
Used in Structural Biology:
As a ligand in double-stranded DNA (dsDNA) activation-induced cytidine deaminase crystallization, 2'-Deoxycytidine 5'-monophosphate sodium salt contributes to the field of structural biology. This application aids in the determination of protein structures and their interactions with DNA, providing insights into the molecular mechanisms of DNA repair and other related processes.
Check Digit Verification of cas no
The CAS Registry Mumber 13085-50-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,8 and 5 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13085-50:
(7*1)+(6*3)+(5*0)+(4*8)+(3*5)+(2*5)+(1*0)=82
82 % 10 = 2
So 13085-50-2 is a valid CAS Registry Number.
