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1310714-78-3

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1310714-78-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1310714-78-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,0,7,1 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1310714-78:
(9*1)+(8*3)+(7*1)+(6*0)+(5*7)+(4*1)+(3*4)+(2*7)+(1*8)=113
113 % 10 = 3
So 1310714-78-3 is a valid CAS Registry Number.

1310714-78-3Downstream Products

1310714-78-3Relevant articles and documents

SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors

Zhou, Gang,Ting, Pauline C.,Aslanian, Robert,Cao, Jianhua,Kim, David W.,Kuang, Rongze,Lee, Joe F.,Schwerdt, John,Wu, Heping,Jason Herr,Zych, Andrew J.,Yang, Jinhai,Lam, Sang,Wainhaus, Samuel,Black, Todd A.,McNicholas, Paul M.,Xu, Yiming,Walker, Scott S.

, p. 2890 - 2893 (2011/06/24)

A novel series of pyridazinone analogs has been developed as potent β-1,3-glucan synthase inhibitors through structure-activity relationship study of the lead 5-[4-(benzylsulfonyl)piperazin-1-yl]-4-morpholino-2-phenyl- pyridazin-3(2H)-one (1). The effect of changes to the core structure is described in detail. Optimization of the sulfonamide moiety led to the identification of important compounds with much improved systematic exposure while retaining good antifungal activity against the fungal strains Candida glabrata and Candida albicans.

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