131497-30-8

Basic information

• Product Name: 1-(3-nitro-phenyl)-5-phenyl-penta-2,4-dien-1-one
• CAS NO: 131497-30-8
• Molecular Weight: 279.295
• Mol File: 131497-30-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(3-nitro-phenyl)-5-phenyl-penta-2,4-dien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-nitro-phenyl)-5-phenyl-penta-2,4-dien-1-one(131497-30-8)
• EPA Substance Registry System: 1-(3-nitro-phenyl)-5-phenyl-penta-2,4-dien-1-one(131497-30-8)

Safety Data

• Hazardous Substances Data: 131497-30-8(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 121-89-1 3-Nitroacetophenone 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 61748-04-7 1-(3-nitrophenyl)-2-(triphenylphosphoranylidene)ethanone 

Downstream Products

• 1315595-94-8 C₂₅H₂₀N₂O₃ 
• 35173-74-1 3,3'-bis-indolyl(phenyl)methane 

Relevant articles and documents

Synthesis, antimicrobial and cytotoxic activity of novel 1,5 benzodiazepine derivatives

In the present study, a series of novel 2-(substituted phenyl)-3-styryl-2,3-dihydro- 1H-benzo [b] [1,4] diazepines (1-12) has been synthesized from 1,5-(disubstituted phenyl)-2,4-pentadien-1-ones (1a-12a). 1,5-(disubstituted phenyl)-2,4-pentadien-1-ones were prepared by condensing cinnamaldehyde with various aromatic ketones in the presence of 20% NaOH as base. Different 1,5-(disubstituted phenyl)-2,4-pentadien-1-ones on cyclisation with o-phenylene diamine in the presence of NaOH as base resulted in 2-(substituted phenyl)-3-styryl-2,3-dihydro-1H-benzo [b] [1,4] diazepine derivatives. The structures of the newly synthesized compounds were characterized by elemental analysis, IR, 1H NMR and mass spectroscopic studies. All titled compounds were screened for their antimicrobial and cytotoxic activities. Most of the compounds showed promising cytotoxic, antibacterial and antifungal activities.

Synthesis, characterization and biological activity studies of some substituted pyrimidine derivatives

A new series of substituted 1-phenyl-3-styryl-4,5-dihydo-1H-pyrazoles (TP1-TP9) has been synthesized by the cyclisation of chalcones with phenyl hydrazine and glacial acetic acid and substituted 4-styryl-pyrimidin-2-ols (LP1-LP9) have been synthesized by the condensation of chalcones with urea in the presence of 40% NaOH as a base. The intermediate substituted 1,5-diphenylpenta-2,4-dien-1-ones were synthesized by condensing cinnamaldehyde with various substituted aromatic ketones in presence of 20% NaOH. The title compounds obtained were characterized by IR, 1H NMR, mass spectral data and were screened for antimicrobial, anticancer and antitubercular activity.

Amberlyst-15 catalysed microwave assisted cross-aldol condensation between ketones and aldehydes under solvent free condition

Amberlyst-15 has been applied as an efficient heterogeneous catalyst for the first time for rapid synthesis of α,α′-bis(arylmethylene) cycloalkanones, α,α′-bis(cinnamylidene)cycloalkanones, ′-cinnamylideneacetophenones and chalcones in very good yield by the reaction between various aldehydes and ketones under microwave irradiation. The new process for the cross-aldol condensation reaction works well in absence of any solvent. The yields are high and the process is environmentally benign.