1315257-23-8Relevant articles and documents
Ruthenium-catalyzed oxidative annulation by cleavage of C-H/N-H bonds
Ackermann, Lutz,Lygin, Alexander V.,Hofmann, Nora
, p. 6379 - 6382 (2011/09/12)
Bond activation in action: Unprecedented ruthenium-catalyzed oxidative annulations of alkynes through cleavage of C-H bonds set the stage for an efficient 1(2H)-isoquinolone synthesis with ample scope (see scheme; tAm=tert-amyl). Mechanistic studies provided strong evidence for a rate-limiting C-H bond metalation through carboxylate assistance. Copyright