131537-31-0 Usage
Fused tricyclic structure
The compound has a three-ring structure formed by the fusion of imidazole and isoquinoline rings.
Nitrogen-containing heterocyclic compound
The compound contains nitrogen atoms within its heterocyclic structure, which contributes to its potential medicinal and pharmaceutical significance.
Interaction with biological targets
The compound has the ability to interact with biological targets, making it a potential candidate for therapeutic applications.
Anticancer activity
2,3-dihydroimidazo[2,1-a]isoquinoline has been identified as a potential anticancer agent and has shown activity against various cancer cell lines.
Valuable building block
The molecular structure and reactivity of the compound make it a valuable building block for the synthesis of other complex organic compounds.
Unique chemical and biological properties
The unique arrangement of atoms in the molecule gives it specific chemical and biological properties that can be further explored for potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 131537-31-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,5,3 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 131537-31:
(8*1)+(7*3)+(6*1)+(5*5)+(4*3)+(3*7)+(2*3)+(1*1)=100
100 % 10 = 0
So 131537-31-0 is a valid CAS Registry Number.
131537-31-0Relevant articles and documents
Catalyst-free ambient temperature synthesis of isoquinoline-fused benzimidazoles from 2-alkynylbenzaldehydes: Via alkyne hydroamination
Mishra, Manisha,Twardy, Dylan,Ellstrom, Clifford,Wheeler, Kraig A.,Dembinski, Roman,T?r?k, Béla
, p. 99 - 108 (2019/01/11)
An efficient environmentally benign route for the synthesis of benzimidazo[2,1-a]isoquinoline has been developed by reacting 2-ethynylbenzaldehyde and related substituted alkynylbenzaldehydes with variously substituted ortho-phenylenediamines and aliphatic amines in ethanol. This method provides a convenient, room temperature, atom-economical, and catalyst-free access to diversely substituted isoquinoline fused benzimidazoles. Regioselectivity of the reaction, as referred to o-phenylenediamines, was confirmed by X-ray crystallography. The reaction was found to occur in three major steps (imine formations, cyclization, and aromatization) and a mechanism has been proposed.
