13249-96-2

Basic information

• Product Name: Naphthalene, 1-(phenylsulfonyl)-
• CAS NO: 13249-96-2
• Molecular Formula: C16H12O2S
• Molecular Weight: 268.336
• Mol File: 13249-96-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Naphthalene, 1-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 1-(phenylsulfonyl)-(13249-96-2)
• EPA Substance Registry System: Naphthalene, 1-(phenylsulfonyl)-(13249-96-2)

Safety Data

• Hazardous Substances Data: 13249-96-2(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 85-46-1 1-Naphthalenesulfonyl chloride 
• 13922-41-3 1-Naphthylboronic acid 
• 873-55-2 sodium benzenesulfonate 
• 90-14-2 1-Iodonaphthalene 
• 780-69-8 triethoxyphenylsilane 
• 98-09-9 benzenesulfonyl chloride 
• 930-69-8 sodium thiophenolate 
• 90-11-9 1-Bromonaphthalene 
• 91-20-3 naphthalene 
• 98-11-3 benzenesulfonic acid 
• 122776-45-8 1-(phenylsulfinyl)naphthalene 
• 7570-98-1 1-naphthyl phenyl sulfide 
• 66003-76-7 Diphenyliodonium triflate 

Relevant articles and documents

A Copper(I)-Catalyzed Sulfonylative Hiyama Cross-Coupling

An air-tolerant Cu-catalyzed sulfonylative Hiyama cross-coupling reaction enabling the formation of diaryl sulfones is described. Starting from aryl silanes, DABSO and aryliodides, the reaction tolerates a large variety of polar functional groups (amines, ketones, esters, aldehydes). Control experiments coupled with DFT calculations shed light on the mechanism, characterized by the formation of a Cu(I)-sulfinate intermediate via fast insertion of a SO2 molecule.

Selective Synthesis of ortho-Substituted Diarylsulfones by Using NHC-Au Catalysts under Mild Conditions

A single-step gold(I)-catalyzed chemoselective protocol to access ortho-substituted diarylsulfones has been established. Acenaphthoimidazolylidene gold complexes are effective catalysts for the arylsulfonylation of boronic acids by potassium metabisulfite (K2S2O5) and diaryliodonium salts to access (poly-)ortho-substituted diarylsulfones even in gram scale. Unlike the transition metal-catalyzed two-component coupling systems, the sterically hindered aryl groups in diaryliodonium salts are preferentially transferred over less bulky ones to form synthetically difficult targets, including those of pharmaceutical importance.

CuI catalyzed sulfonylation of organozinc reagents with sulfonyl halides

In this study, a facile CuI catalyzed synthesis of sulfones involving a nucleophilic addition of functionalized organozinc reagents to organic sulfonyl chlorides is realized. This reaction proceeds efficiently at room temperature, giving rise to various functional group substituted sulfones, generally in moderate to high yields. The method provides a novel, simple, and promising strategy for functionalized sulfone synthesis in the research field of sulfur chemistry. the Partner Organisations 2014.