133160-98-2

Basic information

• Product Name: 4-nitro-benzoic acid-[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]
• Synonyms: 4-nitro-benzoic acid-[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]
• CAS NO: 133160-98-2
• Molecular Weight: 314.341
• Mol File: 133160-98-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-nitro-benzoic acid-[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide](CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-benzoic acid-[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide](133160-98-2)
• EPA Substance Registry System: 4-nitro-benzoic acid-[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide](133160-98-2)

Safety Data

• Hazardous Substances Data: 133160-98-2(Hazardous Substances Data)

Upstream product

• 1184662-59-6 3-(4-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-one 
• 90-82-4 pseudoephedrine 
• 122-04-3 4-nitro-benzoyl chloride 
• 299-42-3 ephedrine 

Downstream Products

• 41958-45-6 4-nitro-benzoic acid-[((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]; N-(4-nitro-benzoyl)-(+)-pseudoephedrine 
• 321-97-1 (1R,2R)-pseudoephedrine 
• 90-82-4 pseudoephedrine 

Relevant articles and documents

Reaction of α,β-alkynylketones with β-amino alcohols: Pseudoephedrine- assisted cleavage of triple bond via formal internal redox process

Reaction of 3-aryl-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-ones with (+)-pseudoephedrine leads to products of alkyne moiety cleavage, namely, 1-(3,4,5-trimethoxyphenyl)ethanone and N-(1-hydroxy-1-phenylprop-2-yl)-N-methylbenzamides. In the course of the process one of alkyne carbons undergoes a formal reduction to a Me group, whereas the other one is oxidized to a C(O)NRR' moiety.