13337-77-4

Basic information

• Product Name: 3-Pyridinecarboxamide, N-(2-oxo-2-phenylethyl)-
• CAS NO: 13337-77-4
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.261
• Mol File: 13337-77-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, N-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, N-(2-oxo-2-phenylethyl)-(13337-77-4)
• EPA Substance Registry System: 3-Pyridinecarboxamide, N-(2-oxo-2-phenylethyl)-(13337-77-4)

Safety Data

• Hazardous Substances Data: 13337-77-4(Hazardous Substances Data)

Upstream product

• 59-67-6 nicotinic acid 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 613-89-8 2-Aminoacetophenone 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 5468-37-1 2-aminoacetophenone hydrochloride 

Downstream Products

• 106590-21-0 3-(5-phenyl-oxazol-2-yl)-pyridine 
• 106950-01-0 5-phenyl-2-(pyridin-3-yl)thiazole 

Relevant articles and documents

Synthesis method of alpha-acylamino ketone compound

The invention discloses a synthesis method of an alpha-acylamino ketone compound, and belongs to the technical field of organic synthesis. The preparation method comprises the following steps: mixingan alkenyl azide compound 1, a carboxylic acid compound 2 and an organic solvent, and heating to react to obtain the alpha-acylamino ketone compound 3. Compared with the prior art, the method has thefollowing advantages: (1) the synthesis process is simple and efficient, no catalyst is needed in the whole process, and the alpha-acylamino ketone compound can be obtained with high yield by dissolving the alkenyl azide compound and the carboxylic acid compound in the solvent and stirring; (2) raw materials are cheap and easy to obtain, reaction conditions are mild, and operation is simple; (3) the substrate is wide in application range and can be used for modifying drug molecules; and (4) the atom economy is high, and the requirements of green chemistry are met.

Combinatorial discovery of novel fluorescent dyes based on Dapoxyl

We have developed a combinatorial method for the fast and effective synthesis of a library based on a known fluorescent dye, Dapoxyl using parallel solution-phase chemistry. By screening the 140 new compounds using fluorescence-based assays, we identified three new fluorescent dyes with novel properties.