134067-56-4

Basic information

• Product Name: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one
• CAS NO: 134067-56-4
• Molecular Formula: C₂₅H₃₁NO₂
• Molecular Weight: 377.5191
• Mol File: 134067-56-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 557°C at 760 mmHg
• Flash Point: 171.2°C
• Density: 1.12g/cm³
• Vapor Pressure: 1.93E-12mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one(134067-56-4)
• EPA Substance Registry System: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one(134067-56-4)

Safety Data

• Hazardous Substances Data: 134067-56-4(Hazardous Substances Data)

Usage

Description

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one is a complex organic compound that belongs to the class of indenoquinolinone compounds. It has a molecular formula of C27H33NO2 and is synthesized for various purposes such as pharmaceutical research, drug development, and other industrial applications. Its precise properties, potential uses, and biological activities would need to be determined through further analysis and studies.

Uses

Used in Pharmaceutical Research:
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one is used as a research compound for exploring its potential applications in the pharmaceutical industry. Its unique chemical structure may offer novel insights and opportunities for drug development.
Used in Drug Development:
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one is also used in the development of new drugs, particularly those targeting specific biological pathways or diseases. Its complex structure may provide a foundation for the creation of new therapeutic agents with improved efficacy and selectivity.
Used in Industrial Applications:
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-7-benzoyl-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-2H-indeno[5,4-f]quinolin-2-one may find use in various industrial applications, such as the synthesis of other complex organic compounds or as an intermediate in the production of specialty chemicals. Its specific role and utility in these applications would depend on further research and development.

Upstream product

• 100-59-4 phenylmagnesium chloride 
• 103335-49-5 S-2-Pyridyl 3-oxo-4-aza-5alpha-androst-1-ene-17beta-thiocarboxylate 
• 138689-15-3 (5α,17β)-N-Methoxy-N-methyl-3-oxo-4-aza-androst-1-ene-17β-carboxamide 

Relevant articles and documents

A new general method for preparation of N-methoxy-N-methylamides. Application in direct conversion of an ester to a ketone

The reaction of an ester with N,O-dimethylhydroxylamine and a suitable organomagnesium reagent or lithium amide base provides a general method for the preparation of N-methoxy-N-methylamides. Application in the direct conversion of a highly hindered ester to a ketone, the azasteroid 5α-reductase inhibitor MK-0434, is described.

7β-substituted-4-aza-5α-androstan-3-ones as 5α-reductase inhibitors

Described are new 7β-substituted 4-aza-5α-androstan-3-ones and related compounds as 5α-reductase inhibitors.

Substituted 4-aza-5α-androstan-ones as 5α-reductase inhibitors

Described are new 16-substituted and 7,16-disubstituted 4-aza-5α-androstan-3-ones and related compounds as 5α-reductase inhibitors.