134169-13-4

Basic information

• Product Name: 1-Butanone, 4-hydroxy-4-[3-(methylsulfonyl)-5-(phenylmethoxy)-4-propoxyphenyl]-1-( 3,4,5-trimethoxyphenyl)-, (S)-
• CAS NO: 134169-13-4
• Molecular Formula: C30H36O9S
• Molecular Weight: 572.676
• Mol File: 134169-13-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 4-hydroxy-4-[3-(methylsulfonyl)-5-(phenylmethoxy)-4-propoxyphenyl]-1-( 3,4,5-trimethoxyphenyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 4-hydroxy-4-[3-(methylsulfonyl)-5-(phenylmethoxy)-4-propoxyphenyl]-1-( 3,4,5-trimethoxyphenyl)-, (S)-(134169-13-4)
• EPA Substance Registry System: 1-Butanone, 4-hydroxy-4-[3-(methylsulfonyl)-5-(phenylmethoxy)-4-propoxyphenyl]-1-( 3,4,5-trimethoxyphenyl)-, (S)-(134169-13-4)

Safety Data

• Hazardous Substances Data: 134169-13-4(Hazardous Substances Data)

Upstream product

• 134169-11-2 1-<3-(methylthio)-4-n-propoxy-5-(benzyloxy)phenyl>-4-(3,4,5-trimethoxyphenyl)butane-1,4-dione 
• 134169-61-2 3-(N,N,N-trimethylammonium)-1-(3,4,5-trimethoxyphenyl)propan-1-one iodide 
• 604-60-4 2,2'-binaphthol 
• 134169-12-3 1-<3-(methylsulfonyl)-4-n-propoxy-5-(benzyloxy)phenyl>-4-(3,4,5-trimethoxyphenyl)butane-1,4-dione 
• 133239-55-1 3-(methylthio)-4-hydroxy-5-(benzyloxy)benzaldehyde 
• 4815-96-7 3-bromo-4-hydroxy-5-benzyloxybenzaldehyde 
• 50773-56-3 3-benzyloxy-4-hydroxybenzaldehyde 
• 133239-56-2 3-(methylthio)-4-n-propoxy-5-(benzyloxy)benzaldehyde 
• 106331-50-4 1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 

Downstream Products

• 134186-90-6 trans-2-(3-benzyloxy-4-propoxy-5-methylsulfonylphenyl)-5-(3,4,5-trimethoxyphenyl)-tetrahydrofuran 
• 143395-23-7 (2S,5R)-2-(3-Benzyloxy-5-methanesulfonyl-4-propoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan 
• 134236-00-3 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-hydroxyphenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 140705-10-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 143395-24-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-(3-bromopropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134235-99-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-(benzyloxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134237-19-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(1-imidazoyl)-n-propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134186-92-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(1-morpholino)-n-propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134236-08-1 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(phosphonooxy)propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134169-24-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<<<3-(dibenzyloxy)phosphoryl>oxy>propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 143395-27-1 (R)-Methoxy-phenyl-acetic acid (S)-2-{3-benzyloxy-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzenesulfonyl}-1-methyl-ethyl ester 
• 143346-10-5 (R)-Methoxy-phenyl-acetic acid (R)-2-{3-benzyloxy-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzenesulfonyl}-1-methyl-ethyl ester 
• 134236-04-7 3-((S)-2-Hydroxy-propane-1-sulfonyl)-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-phenol 
• 134169-29-2 3-((R)-2-Hydroxy-propane-1-sulfonyl)-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-phenol 

Relevant articles and documents

Development, Synthesis, and Biological Evaluation of (-)-trans-(2S,5S)-2--4-n-propoxy-5-(3-hydroxypropoxy)-phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a Potent Orally Active Platelet-Activating Factor (PAF) Antagonist and

(-)-trans-(2S,5S)-2--4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (10) is one of the most potent platelet-activating factor (PAF) antagonists in vitro and in vivo developed to date.This diaryl

2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group, Y is an alkyl or substituted alkyl group, R6 is an alkyl or a substituted alkyl group and the substituents at positions 3, 4 or 5 are acyclic.