1352210-55-9Relevant articles and documents
Formation of five- and seven-membered rings enabled by the triisopropylsilyl auxiliary group
Usanov, Dmitry L.,Yamamoto, Hisashi
, p. 414 - 417 (2012/02/15)
A highly convenient synthetic pathway to 2-indanones from aldehydes was established. The introduction of a triisopropylsilyl group greatly facilitated Meinwald rearrangement of the intermediate epoxides and alleviated the necessity of polysubstitution for the clean formation of indenes and cyclopentadienes via cyclodehydration of allylic alcohols; unprecedented freedom with respect to the product structure was thus achieved. The developed methodology could also be applicable to the formation of seven-membered rings leading to dibenzo[7]annulenes and dibenzosuberones.
