135782-24-0 Usage
Description
Morpholine-2-carbonitrile is an organic compound with the molecular formula C5H8N2. It is a heterocyclic compound featuring a morpholine ring, which is a six-membered ring containing two nitrogen atoms and four carbon atoms. The carbonitrile group (-CN) is attached to the second carbon of the morpholine ring, giving it unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
Morpholine-2-carbonitrile is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its ability to form amide derivatives allows for the development of potent antagonists targeting the LFA-1/ICAM-1 interaction, which plays a crucial role in immune response and inflammation. Structure-activity relationship (SAR) studies involving Morpholine-2-carbonitrile have led to the discovery of novel and effective therapeutic agents for treating conditions such as autoimmune diseases and inflammatory disorders.
Additionally, Morpholine-2-carbonitrile can be utilized in the development of other bioactive molecules with potential applications in different areas of the pharmaceutical industry, including the creation of new drugs for pain management, central nervous system disorders, and cardiovascular diseases. Its versatility as a synthetic building block makes it a valuable component in the design and synthesis of a wide range of pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 135782-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,8 and 2 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 135782-24:
(8*1)+(7*3)+(6*5)+(5*7)+(4*8)+(3*2)+(2*2)+(1*4)=140
140 % 10 = 0
So 135782-24-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H8N2O/c6-3-5-4-7-1-2-8-5/h5,7H,1-2,4H2
135782-24-0Relevant articles and documents
The synthesis of 2-morpholine carboxylic acid derivatives and their elaboration to 1-aza-4-oxabicyclo[3.3.1]nonan-6-one
King,Martin
, p. 2281 - 2284 (2007/10/19)
Two syntheses of novel 2-morpholine carboxylic acid derivatives are described. The esters were converted into 1-aza-4-oxabicyclo[3.3.1]nonan-6-one, the first example of this ring system, which was further elaborated to the ortho-methoxy benzamide derivative (2).
