1365268-05-8

Basic information

• Product Name: 1-benzenesulfonyloxy-4-chloro-9,10-anthraquinone
• CAS NO: 1365268-05-8
• Molecular Weight: 398.823
• Mol File: 1365268-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzenesulfonyloxy-4-chloro-9,10-anthraquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzenesulfonyloxy-4-chloro-9,10-anthraquinone(1365268-05-8)
• EPA Substance Registry System: 1-benzenesulfonyloxy-4-chloro-9,10-anthraquinone(1365268-05-8)

Safety Data

• Hazardous Substances Data: 1365268-05-8(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 82-42-8 4-chloro-1-hydroxyanthraquinone 
• 98-09-9 benzenesulfonyl chloride 

Relevant articles and documents

Anti HIV-1 agents 7. Discovery of 1-hydroxy-4-chloro-9,10-anthraquinone derivatives as New HIV-1 Inhibitors in Vitro

In continuation of our program aimed at the discovery and development of anti-HIV-1 agents, six 1-hydroxy-4- chloro-9, 10-anthraquinone derivatives (3-8) were prepared and preliminarily evaluated as HIV-1 inhibitors in vitro for the first time. Compounds 4 and 6 exhibited the potent anti-HIV-1 activities with EC50 values of 9.81 and 17.90 μg/mL, and TI values of >13.58 and >11.17, respectively. It demonstrated that introduction of the alkylacyloxy or alkylsulfonyloxy group at the 1-position of 1-hydroxy-4-chloro-9,10- anthraquinone could afford the more promising and potent compound than that having arylacyloxy or arylsulfonyloxy one.