137345-97-2

Basic information

• Product Name: Benzene, 2-azido-4-chloro-1-methoxy-
• CAS NO: 137345-97-2
• Molecular Formula: C7H6ClN3O
• Molecular Weight: 183.597
• Mol File: 137345-97-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 2-azido-4-chloro-1-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-azido-4-chloro-1-methoxy-(137345-97-2)
• EPA Substance Registry System: Benzene, 2-azido-4-chloro-1-methoxy-(137345-97-2)

Safety Data

• Hazardous Substances Data: 137345-97-2(Hazardous Substances Data)

Upstream product

• 623-12-1 4-chloromethoxybenzene 
• 95-03-4 5-chloro-2-methoxyaniline 
• 89694-48-4 5-chloro-2-methoxyphenyl boronic acid 

Downstream Products

• 95-03-4 5-chloro-2-methoxyaniline 
• 690638-34-7 1-(2'-methoxy-5'-chlorophenyl)-5-(4'-nitrophenyl)-1H-1,2,3-triazole-4-carboxylic acid 
• 690638-42-7 1-(2'-methoxy-5'-chlorophenyl)-5-(4'-chlorophenyl)-1H-1,2,3-triazole 
• 859408-82-5 (1-(5-chloro-2-methoxyphenyl)-1H-1,2,3-triazol-4-yl)(phenyl)methanone 
• 859408-90-5 (1-(5-chloro-2-hydroxyphenyl)-1H-1,2,3-triazol-4-yl)(phenyl)methanone 
• 690638-35-8 1-(2'-methoxy-5'-chlorophenyl)-5-(4'-nitrophenyl)-1H-1,2,3-triazole 
• 1217352-61-8 2-[[3-(5-chloro-2-methoxyphenyl)triaz-2-enylidene](dimorpholin-4-yl)phosphoranyl]-3-pyrrolidin-1-yl-but-2-enenitrile 

Relevant articles and documents

Combinatorial synthesis of new fluorescent scaffolds using click chemistry

Azides and acetylenes are bio-orthogonal functional groups that can be readily coupled using copper(I)- or ruthenium(II)- catalyzed 1,3-dipolar cycloaddition reactions. Using non-fluorescent aromatic azides and aromatic acetylenes, covering a range of electron rich and poor building blocks, the Huisgen cycloaddition afford 1,4-disubstituted or 1,5-disubstituted 1,2,3-triazoles. Using a combinatorial approach by running reaction in parallel in polypropylene 96-well plates we discovered several new fluorescent 1,2,3-triazoles scaffolds. These compounds show diverse interactions with biomolecules that could find applications in biology in, for example, fluorescence microscopy or biomolecule quantification.

Fast dye salts provide fast access to azidoarene synthons in multi-step one-pot tandem click transformations

This study examined whether commercially available diazonium salts could be used as efficient aromatic azide precursors in one-pot multi-step click transformations. Seven different diazonium salts, including Fast Red RC, Fast Blue B, Fast Corinth V and Va

Hypervalent iodine-induced nucleophilic substitution of para-substituted phenol ethers. Generation of cation radicals as reactive intermediates

A novel hypervalent iodine induced nucleophilic substitution of para-substituted phenol ethers in the presence of a variety of nucleophiles is described. UV and ESR spectroscopic studies indicate that this reaction proceeds via cation radicals, [ArH?+], as reactive intermediates generated by single-electron transfer (SET) from a charge-transfer (CT) complex of phenol ethers with phenyliodine(III) bis(trifluoroacetate) (PIFA). This is the first case that involves a radical intermediate on hypervalent iodine oxidations of aromatic compounds.