1374507-24-0 Usage
General Description
N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine is a synthetic organic chemical compound with the molecular formula C12H9ClF3N5. It belongs to the class of amines and is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is an important building block in drug discovery and development due to its versatile reactivity and unique structural properties. This chemical is a potent and selective inhibitor of certain enzymes and has potential applications in the treatment of cancer, infectious diseases, and other medical conditions. Its precise molecular structure and chemical properties make it a valuable tool in chemical research and drug design.
Check Digit Verification of cas no
The CAS Registry Mumber 1374507-24-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,5,0 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1374507-24:
(9*1)+(8*3)+(7*7)+(6*4)+(5*5)+(4*0)+(3*7)+(2*2)+(1*4)=160
160 % 10 = 0
So 1374507-24-0 is a valid CAS Registry Number.
1374507-24-0Relevant articles and documents
Tyrosine Kinase Inhibitor And Uses Thereof
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Paragraph 0419-0420, (2017/05/15)
Disclosed is a compound of Formula (I) or a pharmaceutically acceptable salt, ester, or solvate thereof, or their stereoisomers, which can be used as tyrosine kinase inhibitor. Also disclosed is a method for preparing the compound, a pharmaceutical composition and a kit comprising the compound, and uses of the compound. The compound can be used as tyrosine kinase inhibitor, or can be used to reduce or inhibit activity of EGFR or mutant thereof, such as EGFR mutant comprising T790M mutation, in a cell, or to treat and/or prevent a disease associated with overactivity of EGFR, such as cancer.
Heteroaryl compounds and uses thereof
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Page/Page column 25, (2016/02/08)
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
HETEROCYCLIC COMPOUNDS AND USES THEREOF
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Paragraph 0161; 0163, (2015/10/05)
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.