1380313-45-0

Basic information

• Product Name: (4S,5R)-4-methyl-5-phenyl-[1,2,3]oxathiazolidine 2,2-dioxide
• Synonyms: (4S,5R)-4-methyl-5-phenyl-[1,2,3]oxathiazolidine 2,2-dioxide
• CAS NO: 1380313-45-0
• Molecular Weight: 213.257
• Mol File: 1380313-45-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5R)-4-methyl-5-phenyl-[1,2,3]oxathiazolidine 2,2-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-4-methyl-5-phenyl-[1,2,3]oxathiazolidine 2,2-dioxide(1380313-45-0)
• EPA Substance Registry System: (4S,5R)-4-methyl-5-phenyl-[1,2,3]oxathiazolidine 2,2-dioxide(1380313-45-0)

Safety Data

• Hazardous Substances Data: 1380313-45-0(Hazardous Substances Data)

Upstream product

• 90-63-1 (RS)-1-hydroxy-1-phenylpropan-2-one 
• 25438-37-3 phenyl(trimethylsiloxy)acetonitrile 
• 1380313-44-9 4-methyl-5-phenyl-5H-[1,2,3]oxathiazole 2,2-dioxide 

Downstream Products

• 492-41-1 (1R,2S)-norephedrine 
• 492-39-7 (1S,2S)-2-amino-1-phenylpropanol 
• 1091606-65-3 (4S,5R)-4-methyl-2,2-dioxo-5-phenyl-2γ6-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Stereoselective synthesis of norephedrine and norpseudoephedrine by using asymmetric transfer hydrogenation accompanied by dynamic kinetic resolution

Each of the enantiomers of both norephedrine and norpseudoephedrine were stereoselectively prepared from the common, prochiral cyclic sulfamidate imine of racemic 1-hydroxy-1-phenyl-propan-2-one by employing asymmetric transfer hydrogenation (ATH) catalyzed by the well-defined chiral Rh-complexes, (S,S)- or (R,R)-Cp*RhCl(TsDPEN), and HCO2H/Et3N as the hydrogen source. The ATH processes are carried out under mild conditions (rt, 15 min) and are accompanied by dynamic kinetic resolution.