1380544-23-9

Basic information

• Product Name: 4,4'-methylenebis(N,N-diethyl-3-methoxyaniline)
• Synonyms: 4,4'-methylenebis(N,N-diethyl-3-methoxyaniline)
• CAS NO: 1380544-23-9
• Molecular Weight: 370.535
• Mol File: 1380544-23-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4'-methylenebis(N,N-diethyl-3-methoxyaniline)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-methylenebis(N,N-diethyl-3-methoxyaniline)(1380544-23-9)
• EPA Substance Registry System: 4,4'-methylenebis(N,N-diethyl-3-methoxyaniline)(1380544-23-9)

Safety Data

• Hazardous Substances Data: 1380544-23-9(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 92-18-2 N,N-diethyl-3-methoxyaniline 

Relevant articles and documents

Copper(II)-catalyzed C-H (sp3) oxidation and C-N cleavage: Synthesis of methylene-bridged compounds using TMEDA as a carbon source in water

A green, simple, and efficient protocol for the selective methylenation via CuCl2/oxygen-mediated C-H (sp3) oxidation and C-N cleavage using tetramethylethylenediamine (TMEDA) as a carbon source has been developed. The reactions were achieved in green solvent water under atmospheric conditions. The protocol exhibited a broad substrate scope including indoles, anilines, pyrroles and 1,3-dicarbonyls. Furthermore, two key intermediates of the reaction were successfully identified and the mechanism was explored. The Royal Society of Chemistry 2013.