1382469-17-1Relevant articles and documents
Role of amphiphilicity in the design of synthetic mimics of antimicrobial peptides with gram-negative activity
Thaker, Hitesh D.,Cankaya, Alper,Scott, Richard W.,Tew, Gregory N.
, p. 481 - 485 (2013)
Two new series of aryl SMAMPs (synthetic mimics of antimicrobial peptides) with facially amphiphilic (FA) and disrupted amphiphilic (DA) topologies were designed and synthesized to directly assess the role of amphiphilicity on their antimicrobial activity
CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
-
, (2013/07/05)
The present invention provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin/low molecular weight heparin derivative.