1388820-11-8

Basic information

• Product Name: N'-(3,4-dimethoxybenzylidene)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetohydrazide
• Synonyms: N'-(3,4-dimethoxybenzylidene)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetohydrazide
• CAS NO: 1388820-11-8
• Molecular Weight: 380.403
• Mol File: 1388820-11-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-(3,4-dimethoxybenzylidene)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(3,4-dimethoxybenzylidene)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetohydrazide(1388820-11-8)
• EPA Substance Registry System: N'-(3,4-dimethoxybenzylidene)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetohydrazide(1388820-11-8)

Safety Data

• Hazardous Substances Data: 1388820-11-8(Hazardous Substances Data)

Upstream product

• 14003-34-0 3-methyl-2-oxo-1,2-dihydroquinoxaline 
• 129886-27-7 ethyl 2-(3-methyl-2-oxo-1,2-dihydroquinoxalin-1-yl)acetate 

Downstream Products

• 1432493-73-6 N-[3-chloro-2-(3,4-dimethoxyphenyl)-4-oxoazetidin-1-yl]-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide 

Relevant articles and documents

Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents

Twelve compounds belonging to series N-[3-chloro-2-oxo-4-(substituted) phenylazetidin-1-yl]-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide (5a-l) were synthesized. These compounds were evaluated for their in vitro antibacterial against E. coli, S. aureus, K. pneumoniae, P. aeruginosa and antifungal activity against C. albicans, A. niger and A. flavus by cup-plate method. Structures of all the newly synthesized compounds were confirmed by their spectral data interpretation. Compound 5g having p-dimethylaminophenyl group on 4-position of azetidinone ring attached to N-atom of acetamido group on 1-position of 3-methyl-1H-quinoxaline-2-one, was found to be active against all the bacterial and fungal strains under investigation.