139088-91-8

Basic information

• Product Name: 2H-Isoindole-2-acetamide, N-(2-chlorophenyl)-1,3-dihydro-1,3-dioxo-
• CAS NO: 139088-91-8
• Molecular Formula: C16H11ClN2O3
• Molecular Weight: 314.728
• Mol File: 139088-91-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-Isoindole-2-acetamide, N-(2-chlorophenyl)-1,3-dihydro-1,3-dioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole-2-acetamide, N-(2-chlorophenyl)-1,3-dihydro-1,3-dioxo-(139088-91-8)
• EPA Substance Registry System: 2H-Isoindole-2-acetamide, N-(2-chlorophenyl)-1,3-dihydro-1,3-dioxo-(139088-91-8)

Safety Data

• Hazardous Substances Data: 139088-91-8(Hazardous Substances Data)

Upstream product

• 95-51-2 o-chloroaniline 
• 1074-82-4 potassium phtalimide 
• 3289-76-7 N-(2-chlorophenyl)chloroacetamide 

Downstream Products

• 29182-97-6 N-methyl-2-bromoacetanilide 

Relevant articles and documents

The synthesis and anticonvulsant activity of some omega-phthalimido-N-phenylacetamide and propionamide derivatives.

In this study, by combining anilide and N', N'-phthaloylglycinamide pharmacophores which are known to produce potent anticonvulsant compounds, sixteen omega-phthalimido-N-phenylacetamide and propionamide derivatives bearing substituents at positions 2 or 2, 6 on N-phenyl ring have been synthesized. The structural confirmation of the title compounds was achieved by interpretation of spectral and analytical data. The anticonvulsant activity of the title compounds was determined against maximal electroshock seizure at 100 mg/kg dose level in mice. The preliminary screening results indicated that omega-phthalimido-N-phenylacetamide and propionamide nuclei have pronounced anticonvulsant activity against maximal electroshock seizure.