1391098-39-7

Basic information

• Product Name: mefenamic acid N,N-dimethylformamide
• CAS NO: 1391098-39-7
• Molecular Weight: 314.384
• Mol File: 1391098-39-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: mefenamic acid N,N-dimethylformamide(CAS DataBase Reference)
• NIST Chemistry Reference: mefenamic acid N,N-dimethylformamide(1391098-39-7)
• EPA Substance Registry System: mefenamic acid N,N-dimethylformamide(1391098-39-7)

Safety Data

• Hazardous Substances Data: 1391098-39-7(Hazardous Substances Data)

Upstream product

• 61-68-7 mefenamic Acid 
• 71-30-7 Cytosine 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Conformational polymorphism in a non-steroidal anti-inflammatory drug, mefenamic acid

For several years, the non-steroidal anti-inflammatory drug mefenamic acid, MA, has been known to exist as dimorphs (I and II). We report a new metastable polymorph (III) of MA obtained during attempted co-crystallization experiments and establish its stability relationship with existing forms. At elevated temperatures I and III convert to II, as evident from DSC experiments. On the basis of the lattice energy calculations in conjunction with thermal analysis, the stability order is proposed to be I > II > III at ambient conditions, whereas at elevated temperature the order is II > I > III. In either condition III is a metastable form and hence transforms to I at ambient conditions and to II at higher temperatures. Also we report the structural studies of a DMF solvate and a cytosine complex.