1396160-78-3

Basic information

• Product Name: C₂₀H₂₂N₂O₅
• CAS NO: 1396160-78-3
• Molecular Weight: 370.405
• Mol File: 1396160-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₂N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₂N₂O₅(1396160-78-3)
• EPA Substance Registry System: C₂₀H₂₂N₂O₅(1396160-78-3)

Safety Data

• Hazardous Substances Data: 1396160-78-3(Hazardous Substances Data)

Upstream product

• 1143-50-6 5,6-dihydro-6,11-dioxomorphanthridine 
• 25542-62-5 6-bromo-hexanoic acid ethyl ester 
• 1396160-75-0 C₂₂H₂₃NO₄ 

Relevant articles and documents

Set-up of a new series of HDAC inhibitors: The 5,11-dihydrodibenzo[b,e] azepin-6-ones as privileged structures

We report here the strategy used in our research group to find a new class of histone deacetylase (HDAC) inhibitors. A series of 5,11-dihydrodibenzo[b,e] azepine-6-ones alkylated on the amide nitrogen with an alkyl chain bearing an hydroxamic acids moiety at the end, has been designed (based upon the general motif for HDAC inhibitors), synthesized and tested. This allowed us to identify a new series of submicromolar HDAC inhibitors, which showed antiproliferative activity on HCT-116 colon carcinoma cells.