1409944-83-7

Basic information

• Product Name: 2-[5-(tert-butyl)-2-methyl-1H-indol-3-yl]-4-phenylthiazole
• CAS NO: 1409944-83-7
• Molecular Weight: 346.496
• Mol File: 1409944-83-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[5-(tert-butyl)-2-methyl-1H-indol-3-yl]-4-phenylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-(tert-butyl)-2-methyl-1H-indol-3-yl]-4-phenylthiazole(1409944-83-7)
• EPA Substance Registry System: 2-[5-(tert-butyl)-2-methyl-1H-indol-3-yl]-4-phenylthiazole(1409944-83-7)

Safety Data

• Hazardous Substances Data: 1409944-83-7(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 21352-99-8 1-(4-phenyl-thiazol-2-yl)-propan-2-one 
• 36600-66-5 4-tert-butylphenylhydrazine hydrochloride 

Relevant articles and documents

Automated multistep continuous flow synthesis of 2-(1H-indol-3-yl)thiazole derivatives

The multistep continuous flow assembly of 2-(1H-indol-3-yl)thiazoles using a Syrris AFRICA synthesis station is reported. Sequential Hantzsch thiazole synthesis, deketalization, and Fischer indole synthesis provides rapid and efficient access to highly functionalized, pharmacologically significant 2-(1H-indol-3-yl)thiazoles. These complex drug-like small molecules are generated in reaction times of less than 15 minutes and in high yields (38-82% over three chemical steps without isolation of intermediates). Georg Thieme Verlag Stuttgart · New York.