1415214-12-8

Basic information

• Product Name: 2,3,4,13-tetrahydro-3,3-dimethyl-13-(2,6-chlorophenyl)-indazolo[2,1-b]phtha-lazine-1,6,11-trione (5g)
• Synonyms: 2,3,4,13-tetrahydro-3,3-dimethyl-13-(2,6-chlorophenyl)-indazolo[2,1-b]phtha-lazine-1,6,11-trione (5g)
• CAS NO: 1415214-12-8
• Molecular Weight: 441.314
• Mol File: 1415214-12-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2,3,4,13-tetrahydro-3,3-dimethyl-13-(2,6-chlorophenyl)-indazolo[2,1-b]phtha-lazine-1,6,11-trione (5g)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,13-tetrahydro-3,3-dimethyl-13-(2,6-chlorophenyl)-indazolo[2,1-b]phtha-lazine-1,6,11-trione (5g)(1415214-12-8)
• EPA Substance Registry System: 2,3,4,13-tetrahydro-3,3-dimethyl-13-(2,6-chlorophenyl)-indazolo[2,1-b]phtha-lazine-1,6,11-trione (5g)(1415214-12-8)

Safety Data

• Hazardous Substances Data: 1415214-12-8(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 126-81-8 dimedone 
• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 
• 88-96-0 phthalamide 

Relevant articles and documents

Solvent-free, sonochemical, one-pot, four-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones and 1H-pyrazolo[1,2-b]phthalazine-diones catalyzed by Fe3O4@SiO2-imid-PMAn magnetic nanoparticles

A practical and green method for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones and 1H-pyrazolo[1,2-b]phthalazine-diones using Fe3O4@SiO2-imid-PMAn nanoparticles as an eco-friendly magnetic catalyst from the four-component condensation, solvent-free reaction of phthalic anhydride, hydrazinium hydroxide, 1,3-diketones, and aldehydes under thermal or ultrasound irradiation at room temperature is described. This new procedure has notable advantages such as operational simplicity, excellent yields, short reaction time, and absence of any tedious work-up or purification. In addition, thermal stability, easy preparation and separation of the catalyst make it a good heterogeneous system and a useful alternative to other heterogeneous catalysts. Also, the catalyst can be easily recovered by a magnetic field and reused for eight consecutive reaction cycles without significant loss of activity.

Efficient one-pot synthesis of 2H-indazolo[2,1-b]phthalazinetrione derivatives with amino-functionalized nanoporous silica (SBA-Pr-NH2) as catalyst

Amino-functionalized SBA-15 (SBA-Pr-NH2) with a pore size of 6 nm has been used as an efficient and reusable heterogeneous solid-base catalyst for preparation of 2H-indazolo[2,1-b]phthalazinetrione derivatives. The procedure involves three-comp

A new inorganic-organic hybrid material Al-SBA-15-TPI/H6P2W18O62 catalyzed one-pot, three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones

A new inorganic-organic hybrid material Al-SBA-15-TPI/H6P2W18O62 was prepared and fully characterized by SEM, XRD, FT-IR, TGA-DTA, and UV-Vis spectroscopic techniques. Then, the prepared nanomaterial was used as a simple, cost-effective, and reusable heterogeneous catalyst for the synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives by a one-pot, three-component condensation reaction of phthalhydrazide, cyclic diones, and aromatic aldehydes under solvent free conditions at 100°C in a short time. This methodology has proven to be efficient and environmentally benign in terms of high yields and low reaction times and offers significant improvements with regard to the scope of transformation and simplicity of operation by avoiding expensive or corrosive catalysts.