141958-01-2Relevant articles and documents
The Discovery of (2S,3S)-cis-2-(diphenylmethyl)-N--1-azabicyclooctan-3-amine as a Novel, Nonpeptide Substance P Antagonist
Lowe, John A.,Drozda, Suzan E.,Snider, R. Michael,Longo, Kelly P.,Zorn, Stevin H.,et al.
, p. 2591 - 2600 (2007/10/02)
We describe the structure-activity relationship development of a series of quinuclidines which culminated in the first potent, selective, nonpeptide substance P (SP) antagonist, (2S,3S)-cis-2-(diphenylmethyl)-N--1-azabicyclo2.2.2