142355-80-4

Basic information

• Product Name: 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine
• Synonyms: 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine;tert-butyl 4-(4-Methoxy-4-oxobut-2-en-1-yl)piperidine-1-carboxylate;tert-butyl 4-(4-methoxy-4-oxobut-2-enyl)piperidine-1-carboxylate
• CAS NO: 142355-80-4
• Molecular Formula: C15H25NO4
• Molecular Weight: 283.366
• Mol File: 142355-80-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 364.054°C at 760 mmHg
• Flash Point: 173.974°C
• Appearance: /
• Density: 1.054g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.481
• PKA: -1.61±0.40(Predicted)
• CAS DataBase Reference: 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine(142355-80-4)
• EPA Substance Registry System: 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine(142355-80-4)

Safety Data

• Hazardous Substances Data: 142355-80-4(Hazardous Substances Data)

Usage

Description

1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine is a chemical compound characterized by the molecular formula C16H27NO3. It is a derivative of piperidine, featuring a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom and a 4-(4-methoxy-4-oxo-2-butenyl) substituent on the piperidine ring. 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine is recognized for its versatility in organic synthesis and its potential applications in the pharmaceutical industry.

Uses

Used in Organic Synthesis:
1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine is used as a building block in organic synthesis for the preparation of various pharmaceuticals and organic compounds. Its ability to undergo a range of chemical transformations makes it a valuable reagent in the field of organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine is utilized as a key intermediate in the synthesis of drugs. Its unique structure and reactivity contribute to the development of new therapeutic agents with potential medicinal properties.
It is important to handle 1-Boc-4-(4-Methoxy-4-oxo-2-butenyl)piperidine with care due to its potential health hazards upon exposure. Proper safety measures should be taken to minimize risks associated with its use in research and industrial applications.

InChI:InChI=1/C15H25NO4/c1-15(2,3)20-14(18)16-10-8-12(9-11-16)6-5-7-13(17)19-4/h5,7,12H,6,8-11H2,1-4H3/b7-5+

Upstream product

• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 142374-19-4 tert-butyl 4-(formylmethyl)piperidine-1-carboxylate 
• 28356-58-3 pyridine-4-acetic acid 
• 51052-78-9 4-piperidinylacetic acid 
• 5927-18-4 trimethyl phosphonoacetate 
• 157688-46-5 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 
• 89151-44-0 4-(2-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 144494-65-5 tirofiban hydrochloride 
• 142355-83-7 4-(1-tert-butoxycarbonylpiperidin-4-yl)-butan-1-ol 
• 142355-81-5 tert-butyl 4-(4-bromobutyl)piperidine-1-carboxylate 
• 142247-38-9 4-[1-(tert-butoxycarbonyl)piperidin-4-yl]butanoic acid 
• 1025892-42-5 4-{4-[4-(2-Carboxy-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 150022-77-8 Methyl 3-[4-(4-N-t-Butyloxycarbonylpiperidin-4-yl)butyloxyphenyl]propanoate 
• 142373-57-7 4-{4-[4-((S)-2-Amino-2-methoxycarbonyl-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 1026353-54-7 4-{4-[4-((S)-2-Acetylamino-2-carboxy-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 1026809-98-2 4-{4-[4-((S)-2-Carboxy-2-propionylamino-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 155727-70-1 4-{4-[4-((S)-2-Carboxy-2-methanesulfonylamino-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 142356-29-4 4-{4-[4-((S)-2-Carboxy-2-pentanoylamino-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 142356-31-8 4-{4-[4-((S)-2-Carboxy-2-hexanoylamino-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 1026652-05-0 4-(4-{4-[(S)-2-Carboxy-2-(propane-1-sulfonylamino)-ethyl]-phenoxy}-butyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1026532-00-2 4-(4-{4-[(S)-2-Methoxycarbonyl-2-(propane-1-sulfonylamino)-ethyl]-phenoxy}-butyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS

The invention is directed to piperidinyl compounds of formula (I) and (II) that selectively bind integrin receptors and methods for treating an integrin mediated disorder, wherein W, R2, Z and q are described in the application.