1427414-73-0

Basic information

• Product Name: 3-[1-((1R,2R)-4,6-difluoro-2-hydroxy-indan-1-yl)-5-(3,3,3-trifluoro-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-benzonitrile
• Synonyms: 3-[1-((1R,2R)-4,6-difluoro-2-hydroxy-indan-1-yl)-5-(3,3,3-trifluoro-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-benzonitrile
• CAS NO: 1427414-73-0
• Molecular Weight: 488.46
• Mol File: 1427414-73-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-[1-((1R,2R)-4,6-difluoro-2-hydroxy-indan-1-yl)-5-(3,3,3-trifluoro-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[1-((1R,2R)-4,6-difluoro-2-hydroxy-indan-1-yl)-5-(3,3,3-trifluoro-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-benzonitrile(1427414-73-0)
• EPA Substance Registry System: 3-[1-((1R,2R)-4,6-difluoro-2-hydroxy-indan-1-yl)-5-(3,3,3-trifluoro-propyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-benzonitrile(1427414-73-0)

Safety Data

• Hazardous Substances Data: 1427414-73-0(Hazardous Substances Data)

Upstream product

• 460-37-7 1,1,1-trifluoro-3-iodopropane 
• 1427415-02-8 3-[1-((1R,2R)-4,6-difluoro-2-hydroxy-indan-1-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-benzonitrile 
• 76-05-1 trifluoroacetic acid 

Relevant articles and documents

Indanyl-Substituted 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridines, Their Use as Medicament, and Pharmaceutical Preparations Comprising Them

The invention relates to substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula (I) act on the TASK-1 potassium channel. The compounds are particularly suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.

INDANYL-SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINES, THEIR USE AS MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM

The invention relates to substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula I act on the TASK-1 potassium channel. The compounds are suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.